Autologous Nanofat Grafting by Injection Versus With Microneedling in Post-burn and Traumatic Atrophic Scars

Not Applicable

Recruiting

• Conditions: Scars
• Interventions: Procedure: injection of autologous nanofat grafting; Procedure: microneedling with autologus nanofat graft

• Registration Number: NCT06566300
• Lead Sponsor: Alexandria University

Brief Summary

This study aims to evaluate the efficiency autologous nanofat injection versus autologous nanofat delivered by microneedling in management of post burn atrophic and traumatic scars.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-08-20
• Study First Submitted QC: 2024-08-20
• Study First Posted: 2024-08-22
• Status Verified: 2024-11
• Study Start: 2024-11-01
• Last Update Submitted: 2024-11-02
• Last Update Posted: 2024-11-05
• Primary Completion: 2025-02
• Study Completion: 2025-02

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• 1. Males and females between 18-60 years old. 2. Post-burn or traumatic atrophic scar > 6 months duration (16). 3. Patients not receiving any treatments for the scar within the past 3 months.

Exclusion Criteria

• 1. Patients with contractures, hypertrophic and keloid scars. 2. Patients with history of bleeding disorders or coagulopathy, or on anticoagulant therpy.

  2. Diabetes and other systemic diseases that may be complicated by the procedure.

  3. Pregnant and lactating females. 5. BMI less than 18.5 6. Patients with scars at the donor site

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
injection of autologous nanofat grafting	injection of autologous nanofat grafting	Two separate scars with similar properties or splitting of one large post-burn atrophic scar. One (part of the) scar will be treated by injection of autologous nanofat grafting and the other (part of the) scar will be treated by microneedling with autologous nanofat graft.
microneedling with autologous nanofat graft	microneedling with autologus nanofat graft	Two separate scars with similar properties or splitting of one large post-burn atrophic scar. One (part of the) scar will be treated by injection of autologous nanofat grafting and the other (part of the) scar will be treated by microneedling with autologous nanofat graft.

Primary Outcome Measures

Name	Time	Method
change in the scar by by the patient and observer scar assessment scale (POSAS).	6 months after the proceedure	patient and observer scar assessment scale score will be uesd

Trial Locations

Locations (1)

Alexandria University; 🇪🇬 Alexandria, Egypt