A Retrospective Study to Assess the Clinical Efficacy and Safety of Trientine in Wilson's Disease Patients
Completed
- Conditions
- Trientine Treatment for Wilson's Disease
- Registration Number
- NCT03299829
- Lead Sponsor
- Excelsior
- Brief Summary
This is a retrospective study to assess the clinical efficacy and safety of trientine in Wilson's disease patients
- Detailed Description
In this retrospective study, the investigators will collect and analyze data from reviewing medical history files of larger and long-term follow-up cohorts with Wilson's disease in Taiwan to assess the efficacy and safety of Trientine in Taiwanese Wilson's Disease patients.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 48
Inclusion Criteria
- Diagnosis of Wilson's disease.
- Male or female patients, aged 3 years to 75 years
Exclusion Criteria
- Patients with comorbidity which is not related to Wilson's disease.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The improvement in liver function Up to 1 year To measure the AST (aspartate aminotransferase), ALT (alanine transaminase), GGT (gamma-glutamyl transpeptidase), Albumin, and Bilirubin level, and compare to the baseline
- Secondary Outcome Measures
Name Time Method The improvement in urine copper excretion Up to 1 year To measure 24-hour urine copper levels during the study period
Trial Locations
- Locations (1)
Chang Gung Memorial Hospital, Linkou
🇨🇳Taoyuan City, Taiwan