Importance of Peritoneal Free Fluid Cultures in Both Perforated and Non-perforated Appendicitis
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- To evaluate the frequency of positive free fluid cultures in both perforated and non-perforated appendicitis
研究概览
简要总结
The purpose of this study is to evaluate the frequency of positive free fluid cultures in both perforated and non-perforated appendicitis. In addition predictors of positive free fluid cultures will be analyzed.
详细描述
Prior to surgery, all patients will receive antibioprophylaxis. In case of free peritoneal fluid, a sample is aspirated and sent for microbiology. A lavage with saline is not necessary. The decision to start postoperative antibiotic is left at the discretion of the surgeon. The decision to leave an abdominal drain is left at the discretion of the surgeon.
The use of a preoperative single dose administration of antibiotics has been extensively studied and found beneficial in the prevention of SSI in appendicitis. However, the use of continued postoperative antibiotics has barely been studied. The sparse evidence that exist does not seem to support its systematic use. During appendectomy the surgeon frequently encounters turbid free fluid, even in non-perforated appendicitis. It is common practice in Belgium to continue antibiotic prophylaxis for 5 days after aspiration and lavage. Although the aspect often seems purulent, it is unknown in what percentage this fluid is contaminated. Also, it is unknown whether after aspiration and lavage intra-abdominal drains are necessary.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 6 Years 至 90 Years(Child, Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Appendicitis (Perforated/ Non-perforated) Free fluid Age: 6 - 90y
排除标准
- •Immunosuppression (recent chemotherapy, chronic use of immunosuppressive medication) Age < 6 and > 90y
结局指标
主要结局
To evaluate the frequency of positive free fluid cultures in both perforated and non-perforated appendicitis
时间窗: 24 hours
In case of free peritoneal fluid, a sample will be aspirated and sent for microbiology.
次要结局
未报告次要终点
