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eft Atrial Appendage Occlusion Study III

Not Applicable
Recruiting
Conditions
Patients with atrial fibrillation/flutter undergoing on-pump cardiac surgery
Registration Number
JPRN-UMIN000019388
Lead Sponsor
Population Health Research Institute
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
4700
Inclusion Criteria

Not provided

Exclusion Criteria

1) Patients undergoing any of the following procedures: a. Off-pump cardiac surgery b. Heart transplant c. Complex congenital heart surgery d. Sole indication for surgery is ventricular assist device insertion e. Previous cardiac surgery (re-operation) f. Mechanical valve implantation 2) Patients who have had a previous placement of a percutaneous LAA closure device

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The first occurrence of ischemic stroke or transient ischemic attack with positive neuroimaging or systemic arterial embolism over the duration of follow-up.
Secondary Outcome Measures
NameTimeMethod
1) total mortality 2) post-operative safety outcomes (chest tube output in the first 24 hours post-surgery, post-operative re-exploration for bleeding in the first 48 hours postsurgery, and 30-day mortality) 3) the incidence of re-hospitalization for heart failure 4) the incidence of major bleeding 5) the incidence of myocardial infarction
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