Clinical Trial of Zirconia and Metal Adhesive Bridges
- Conditions
- Missing Teeth
- Interventions
- Procedure: Zirconia-based adhesive bridgeProcedure: Metal-based adhesive bridge
- Registration Number
- NCT01347177
- Lead Sponsor
- Queen Mary University of London
- Brief Summary
Adhesive bridges are becoming popular in patients with congenitally missing teeth and these are type of bridges that can be done with only minimal or with no preparation to replace the missing tooth/teeth. The best clinical gain is the minimal tooth preparation or no need for the removal of tooth substance. Treatment for this type of bridges does not usually require anaesthesia. In addition, adhesive bridges can provide reasonable aesthetical outcome with minimal cost and reduced chair time.
The biggest issue is that high failure rate in the long term, and gray colour shining through the metal wing cemented onto the abutment tooth. This can compromise the aesthetical outcome. The aesthetical problem can be solved by the use of zirconia all ceramic material to construct the bridge.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
- Male or female ≥ 18 years of age
- Has a maximum of 2 units requiring placement
- Is a regular dental attendee and agree to return for assessments
- Written subject informed consent (IC) for this protocol will be obtained prior to study enrolment. Each subject will be required to sign and date the IC form prior to their participation
- Sound or minimally restored abutment(s)
- The presence of any periodontal pocket depths equal or above 4 mm with active periodontal disease
- Any history of adverse reaction to clinical materials to be used in this study
- They are pregnant or had serious medical condition that may interfere with the dental treatment
- Acquired tooth loss more than 2 units requiring replacement
- Participants who have parafunctional habits
- Severe Class II Div II cases
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Zirconia-based adhesive bridges Zirconia-based adhesive bridge Patients in this group will be treated with the employment of zirconia-based adhesive bridges to replace the missing tooth/teeth. Metal-based adhesive bridges Metal-based adhesive bridge Patients in this group will be treated with the employment of metal-based adhesive bridges.
- Primary Outcome Measures
Name Time Method Clinical survival of adhesive bridges 5 Years Evaluation of clinical survival: participants will be evaluated according to the modified USPHS criteria. The evaluation criteria will include: retention, framework fracture, veneering fracture, marginal adaptation, recurrent caries and colour match. The examination will be after one to two weeks, after 3, 6, 9, 12 and 18 months, 2, 3, 4 and 5 years. The evaluation will also include the biological complication. Plaque, gingival index, periodontal probing depth and gingival recession will be evaluated around the abutments and compared to a control tooth
- Secondary Outcome Measures
Name Time Method Marginal discrepancy evaluation. After cementation Marginal discrepancy will be evaluated by means of Scannining Electron Microscope (SEM) after cementation.
Economic evaluation 5 years Economic evaluation will be run in parallel to the study and will include the overall cost of the two treatments.
Quality of life, aesthetic outcome. 18 months The patients will be requested to fill the OHIP-14 and the VAS questionnaires after one week to two weeks, after 3, 6, 9, 12 and 18 months in order to assess the quality of their lives and their aesthetic outcome after having the bridge.
Trial Locations
- Locations (1)
Barts and The London, School of Medicine and Dentistry
🇬🇧London, United Kingdom