MedPath

Intra- and Interrater Reliability of Quantitative Ultrasound Assessment of Gastric Content in Term Parturients Before Elective Caesarean Delivery

Not Applicable
Completed
Conditions
Pregnancy
Respiratory Aspiration of Gastric Content
Interventions
Device: Ultrasound
Registration Number
NCT05946447
Lead Sponsor
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Brief Summary

The presence of solid food or fluid residue in the stomach is always a major concern when patients require medical procedures under sedation or general anesthesia, due to the high risk of pulmonary aspiration of the stomach contents. This is especially important in emergency procedures, when a fasting period could not be observed. Pulmonary aspiration of gastric content is a serious perioperative complication of obstetric anesthesia, and it is associated with morbidity and mortality. Information from a bedside ultrasound assessment of the stomach may be a very useful resource to decide whether it's safe to proceed, cancel or delay a surgical procedure. The ultrasound assessment of the stomach content has shown to be very feasible and practical in non-pregnant patients. However, it has not been determined whether the competence reached by anesthesiologists in non-pregnant subjects can be transferred to the obstetric population, especially in term pregnant patients where it could be difficult to identify the stomach because of the presence of the gravid uterus. Although quantitative assessment of the gastric antrum cross-sectional area in terms of intra- and interrater reliability has been evaluated in non-pregnant adults, it remains to be evaluated in pregnant patients. Furthermore, it has not been determined whether the performance of novice operators is comparable to expert operators in the gastric quantitative assessment. This study aims to determine whether trained anesthesiologists can reliably assess the stomach content of pregnant patients by ultrasound, evaluating the inter- and intra-rater reliability of quantitative gastric ultrasound in term pregnant patients comparing anesthesiologists of different level of expertise. The investigators hypothesize a substantial to almost perfect agreement in the intra- and interrater reliability of the antral cross-sectional area among raters in term pregnant patients scheduled for elective cesarean delivery.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
30
Inclusion Criteria
  • non-laboring term pregnant women scheduled for cesarean delivery under neuraxial anesthesia
  • ≥37 weeks gestational age
  • ≥18 years of age
  • ASA physical status II-III
  • weight 50 to 120 kg
  • height ≥150 cm
  • ability to understand the rationale of the study evaluations.
Exclusion Criteria
  • multiple pregnancy
  • known (reported by the study subject) anomalous anatomy of the upper gastrointestinal tract
  • previous surgical procedures on the esophagus, stomach or upper abdomen
  • patients not following our institutional fasting instructions (8 hours after a meal and 2 hours for clear liquids)

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Gastric UltrasoundUltrasoundUltrasound measurements of the antrum will be recorded.
Primary Outcome Measures
NameTimeMethod
Antral cross-sectional area (right lateral decubitus)5 minutes

The cross-sectional area (in centimeters squared) of the antrum will be measured with the patient in right lateral decubitus position, using the ultrasound machine. Measurements will be done 3 times, by 2 investigators.

Antral cross-sectional area (supine position)5 minutes

The cross-sectional area (in centimeters squared) of the antrum will be measured with the patient in supine position, using the ultrasound machine. Measurements will be done 3 times, by 2 investigators.

Secondary Outcome Measures
NameTimeMethod
Inter-rater reliability calculation5 minutes

Inter-rater reliability will be calculated using the 3 measurements, between raters.

Grading of stomach contents5 minutes

Grading scale: grade 0 means no gastric contents are visualized in supine and the right lateral decubitus, grade 1 means gastric contents are visualized in right lateral decubitus but not in supine decubitus, and grade 2 means gastric contents are visualized in both positions

Gastric volume (supine position)5 minutes

Gastric volume (ml) will be estimated using the antral cross-sectional area obtained with the patient in supine position

Intra-rater reliability calculation5 minutes

Intra-rater reliability will be calculated using the 3 measurements, for each rater.

Gastric volume (right lateral decubitus)5 minutes

Gastric volume (ml) will be estimated using the antral cross-sectional area obtained with the patient in right lateral decubitus.

Trial Locations

Locations (1)

Mount Sinai Hospital

🇨🇦

Toronto, Ontario, Canada

© Copyright 2025. All Rights Reserved by MedPath