A registry enabled antimicrobial stewardship quality improvement project in ICUs in India.

Not Applicable

Conditions: Health Condition 1: Z163- Resistance to other antimicrobialdrugs

Registration Number: CTRI/2022/11/047161

Lead Sponsor: The George Institue for Global Health India

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Open to Recruitment

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

Invitation to participate will be open to all intensive care units within the participating hospitals of the IRIS network. Participation from a minimum of 4 and a maximum of 8 ICUs is sought. These are a mix of public, private and mixed setting hospitals, representative of all sectors catering to critical care in India.

Exclusion Criteria

ICUs which have established registry data collection of core, and daily Q (including quality indicators) to a completeness of >95% compliance will be selected.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. The amounts of antimicrobial consumption by each ICU will be presented as defined daily doses (DDD) [36] and days of therapy (DOT) [37] per 1000 patient days and over all prescribing rate. <br/ ><br>2. To provide assessment of the antimicrobial spectrum across various encounter types, an antimicrobial spectrum index tool will be applied to antimicrobial use data <br/ ><br>3. The WHO policy guidance on integrated antimicrobial stewardship activities will be used to assess the ICU preparedness for AMS. <br/ ><br>3. Guideline congruent therapy <br/ ><br>4. Culture and sensitivity patterns. <br/ ><br>5. In-depth interviews and FGD to identify human and organizational factors influence antimicrobial prescribing practices and concordance with existing AMS guidelines in the ICUTimepoint: Based on Objectives for each Research Question (RQ) <br/ ><br>RQ 1- 11 months <br/ ><br>RQ 2- 11 months <br/ ><br>RQ 3- 12 months <br/ ><br>

Secondary Outcome Measures