Luteal Supplementation With Rec-LH After GnRH-agonist Triggering in In Vitro (IVF)
- Registration Number
- NCT00954811
- Lead Sponsor
- Universitair Ziekenhuis Brussel
- Brief Summary
Our aim is to access whether we can achieve equivalent pregnancy rates by the addition of six doses of luteal support with recLH after agonist triggering for IVF cycles in the absence of OHSS.
- Detailed Description
Whether pregnancy outcome after GnRH-agonist triggering could be improved by adding luteal recLH support plus progesterone, compared to that observed after ovulation triggering with HCG in GnRH antagonist stimulated cycles.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 40
Inclusion Criteria
- < 36years,
- single blastocystET,
- FSH < 12
Exclusion Criteria
- endometriosis,
- 3 and 4,
- pco,
- frozen sperm
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description HCG for ovulation triggering and luteal progesterone progesterone 600mg conventional triggering with HCG and conventional luteal support with progesterone Agonist triggering and rec-LH luteal support plus progesterone 300IU rec-LH new method of triggering with GnRH-agonist and proof of concept intervention with novel way of luteal support with rec-LH plus the usual co-treatment with progesterone
- Primary Outcome Measures
Name Time Method pregnancy occurrence, pregnancy loss 14 days after OPU
- Secondary Outcome Measures
Name Time Method hormone levels, OHSS, endometrium 14 days after oocyte pick up
Trial Locations
- Locations (1)
Centre for Reproductive Medicine, UZ Brussel
🇧🇪Brussels, Jette, Belgium