Pilot Investigation of Dual Energy CT Imaging on an Online Adaptive Radiation Therapy System
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Image quality- Mean
研究概览
简要总结
This study is being done to see if researchers can find a better way to image a patient's tumor during radiation treatment.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •* Patients with pelvis or genitourinary (GU) cancer requiring standard of care radiotherapy treatment
- •All adults, defined as individuals of 18 years of age or greater
- •Radiotherapy treatment will be performed on the Varian Ethos radiotherapy system
- •Ability to understand and the willingness to sign a written informed consent
排除标准
- •* Minors, defined as individuals less than 18 years of age
- •Pregnant or nursing female
研究组 & 干预措施
Observational
Patients undergo lower beam energy CBCT scan once during standard of care radiation therapy on study.
干预措施: Non-Interventional Study (Other)
结局指标
主要结局
Image quality- Mean
时间窗: Up to 2 years
The primary analysis will compare imaging quality endpoints processed by DE-CBCT and the standard of care SE-CBCT, with the latter representing the standard clinical acquisition. Descriptive statistics will be computed for the image quality metrics from each imaging modality and for the difference in metrics between the modalities. A paired t-test or Wilcoxon signed-rank test will compare the distribution of the image quality metrics between DE-CBCT and standard of care SE-CBCT. Secondary analysis will compare image quality endpoints between DE-CBCT and standard of care conventional planning CT.
Image quality- median
时间窗: Up to 2 years
The primary analysis will compare imaging quality endpoints processed by DE-CBCT and the standard of care SE-CBCT, with the latter representing the standard clinical acquisition. Descriptive statistics will be computed for the image quality metrics from each imaging modality and for the difference in metrics between the modalities. A paired t-test or Wilcoxon signed-rank test will compare the distribution of the image quality metrics between DE-CBCT and standard of care SE-CBCT. Secondary analysis will compare image quality endpoints between DE-CBCT and standard of care conventional planning CT.
次要结局
未报告次要终点