Gastric-type Endocervical Adenocarcinoma: a Population-based Cohort Study

Completed

• Conditions: Uterine Cervical Neoplasms; Surgery; Therapy; Locally Advanced Cervical Carcinoma

• Registration Number: NCT06897306
• Lead Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Brief Summary

This study aims to collect data of patients with Gastric-type Endocervical Adenocarcinoma from the SEER database, analyze the related prognostic factors and treatment patterns of Gastric-type Endocervical Adenocarcinoma, and explore the impact of surgical treatment on the prognosis of locally advanced Gastric-type Endocervical Adenocarcinoma.

Detailed Description

This study aims to collect data of patients with Gastric - type Endocervical Adenocarcinoma from the SEER database, analyze the related prognostic factors and treatment patterns of patients with Gastric - type Endocervical Adenocarcinoma, and explore the impact of surgical treatment on the prognosis of locally advanced Gastric - type Endocervical Adenocarcinoma.

Study subjects: Patients diagnosed with Gastric - type Endocervical Adenocarcinoma were identified using the SEER database and SEER\*Stat 8.4.2 software. The search scope was the "SEER Research Plus Data, 17 Registries, Nov 2021 sub (2000 - 2019)" database, and the screening criteria included "Site and Morphology, Analytic Behavior Recode = Malignant" and "Site and Morphology, ICD - O - 3 / WHO 2008 Recode Site = Cervix". Patients with cervical Gastric - type Endocervical Adenocarcinoma were selected from the database.

Outcome measures: Overall survival (OS): The time from diagnosis to death of the patient.

Study Timeline

• Study Start: 2024-10-01
• Primary Completion: 2024-11-01
• Study Completion: 2025-01-20
• Status Verified: 2025-02
• Study First Submitted: 2025-02-06
• Study First Submitted QC: 2025-03-20
• Last Update Submitted: 2025-03-20
• Study First Posted: 2025-03-26
• Last Update Posted: 2025-03-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 317

Inclusion Criteria

• Patients diagnosed with Gastric - type Endocervical Adenocarcinoma were identified using the SEER database and SEER*Stat 8.4.2 software. The search scope was the "SEER Research Plus Data, 17 Registries, Nov 2021 sub (2000 - 2019)" database. The screening criteria included "Site and Morphology, Analytic Behavior Recode = Malignant" and "Site and Morphology, ICD - O - 3 / WHO 2008 Recode Site = Cervix". Patients with Gastric - type Endocervical Adenocarcinoma in the database were selected.

Exclusion Criteria

• Patients with a survival time of 0 or unknown.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Overall survival (OS)	The time from diagnosis to death of the patient，Assessed up to 227 months	The time from diagnosis to death of the patient.

Secondary Outcome Measures

Name	Time	Method
Vital status recode(study cutoff used)	up to 227 months	Any patient that dies after the follow-up cut-off date is recoded to alive as of the cut-off date.

Trial Locations

Locations (1)

The Sun Yat-Sen Memorial Hospital of Sun Yat-Sen Universit; 🇨🇳 Guangzhou, Guangdong, China