COMPARATIVE STUDY BETWEEN 1% ALENDRONATE GEL AND 1% METFORMIN GEL IN THE TREATMENT OF PYORRHEA.
- Conditions
- Health Condition 1: K053- Chronic periodontitisHealth Condition 2: K053- Chronic periodontitis
- Registration Number
- CTRI/2021/04/032472
- Lead Sponsor
- Terna Dental college
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 13
1.Patients with periodontal disease with a possible indication for flap surgery and having at least two intra bony defects, one on either side of the same arch, with interproximal probing depth (PD) of at least 5 mm or more after phase I therapy.
2.Patients maintaining proper oral hygiene status.
3.Systemically healthy patients.
4.Patients who give informed consent to participate in the study.
1.Pregnant and lactating females.
2.Patients consuming tobacco in any form.
3.Patients who have undergone periodontal surgical therapy in the last 6 months in the same site.
4.Systemic disease or other conditions that could influence the periodontal status.
5.Allergy to bisphosphonates or history of their systemic use.
6.Unwillingness to return for follow ââ?¬â??up.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction in Probing pocket depth (PPD) and, gain in relative attachment level (RAL),change in height of alveolar bone crest and bone fill.Timepoint: Baseline <br/ ><br>3 month <br/ ><br>6 month <br/ ><br>
- Secondary Outcome Measures
Name Time Method Reduction in Probing pocket depth (PPD) and gain in relative attachment level (RAL), change in height of alveolar bone crest and bone fill between the sites treated with 1% alendronate gel or with 1% metformin gel.Timepoint: Baseline <br/ ><br>3 month <br/ ><br>6 month