Comparing the effect of sevelamer carbonate and sevelamer hydrochloride on blood level of phosphate, Ca, ph, bicarbonate and gastrointestinal complications in patients undergoing maintenance hemodialysis

Phase 3

Conditions: Calcium, Phosphorus, PH, Bicarbonate and Gastrointestinal Complications in Hemodialysis Patients.
Chronic kidney disease, stage 4 (severe)

Registration Number: IRCT20141016019554N13

Lead Sponsor: Zanjan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 44

Inclusion Criteria

Patients who undergo dialysis three sessions each week for four hours each day.
Their blood phosphorus level is higher than 5.5 mg / dL.

Exclusion Criteria

Patients who have not taken limited Phosphorus diet.
Patients who lose their ability to participate during the study
Patients who are absent from dialysis session
Patients who break their access for some reason
Patients who have taken the medication inappropriately.
Patients with a history of primary hyperparathyroidism or history of parathyroidectomy.
Patients with a history of gastrointestinal diseases include peptic ulcer, reflux, and constipation
Patients with a history of congestive heart failure (due to electrolyte imbalance)
Patients with chronic obstructive pulmonary disease (COPD) (due to acid and basis disorders).

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood Calcium. Timepoint: at beginning of intervention and 1 month later. Method of measurement: measurement will be carried out by hospital laboratory.;Blood Phosphorus. Timepoint: at beginning of intervention and 1 month later. Method of measurement: measurement will be carried out by hospital laboratory.;Blood pH. Timepoint: at beginning of intervention and 1 month later. Method of measurement: measurement will be carried out by hospital laboratory.;Blood Bicarbonate levels. Timepoint: at beginning of intervention and 1 month later. Method of measurement: measurement will be carried out by hospital laboratory.

Secondary Outcome Measures