Trial of management of borderline and other low-grade abnormal smears

Not Applicable

Completed

• Conditions: Obstetrics and gynaecology; Urological and Genital Diseases; Abnormal findings in specimens from female genital organs

• Registration Number: ISRCTN34841617
• Lead Sponsor: Medical Research Council (MRC) (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2000-10-25
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 4483

Inclusion Criteria

1. An index smear which indicates mild dyskaryosis, or an index smear which indicates borderline dyskaryosis and a repeat smear taken 6 months later which shows borderline or mild dyskaryosis
2. Resident in Grampian Health Board Area, Tayside Health Board Area or in the Nottingham area with their smear processed by the Nottingham Cervical Screening Laboratory
3. Aged 20-59 years
4. Prior to the index smear, not have had an abnormal smear within the past 3 years
5. Not have had previous treatment for suspected cervical lesions
6. Not be pregnant
7. Not intend to move from the trial areas in the 3-year period following enrolment

Exclusion Criteria

Exclusions from R2: If colposcopy is unsatisfactory because the squamo-columnar junction is not visible, the woman will not be randomised but will be treated according to local clinical practice

Study & Design

• Study Type: Interventional
• Study Design: Not specified