NCT06484634已完成不适用
Role of Low-Molecular-Weight Heparin in Unexplained Recurrent Pregnancy Loss
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 175
- 试验地点
- 1
- 主要终点
- Efficacy of Low-Molecular-Weight Heparin
研究概览
简要总结
Using low-molecular-weight heparin (LMWH), outcomes such as live birth rate and the occurrence of pregnancy complications are some of the variables reported in some studies, with varying degrees of success. The present study aimed to compare the role of LMWH in unexplained recurrent pregnancy loss.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 44 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Pregnant females between 18 and 44 years of age
- •Gestational age above 8 weeks
- •A history of ≥3 consecutive first trimester pregnancy losses
排除标准
- •Patients with systemic lupus erythematosus
- •Positive IgG and IgM anticardiolipin antibodies
- •Positive for thrombophilia screening
- •Any platelet function abnormality or a previous thromboembolic event requiring anticoagulant therapy (including heparin, aspirin or warfarin)
- •Sensitive to acetylsalicylic acid, heparin, or warfarin
- •Patients with any genetic, anatomical, or hormonal cause of recurrent pregnancy loss
研究组 & 干预措施
LMWH Group
Experimental
Women received a daily dose of 40 mg of Low Molecular Weight Heparin subcutaneously.
干预措施: Low molecular weight heparin (Drug)
结局指标
主要结局
Efficacy of Low-Molecular-Weight Heparin
时间窗: 32 weeks
Efficacy was labeled as yes in terms of live births after the age of viability, i.e., 24 weeks of gestation.
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
已完成
2 期
Low-molecular-weight Heparin (LMWH) Versus Unfractionated Heparin (UFH) in Pregnant Women With Recurrent Abortion Secondary to Antiphospholipid SyndromeRecurrent AbortionNCT01051778Cairo University60
Unknown
4 期
Effect of LMWH on Pregnancy Outcome in Women With Multiple Failures of IVF-ETInfertilityNCT03701750Shenzhen Zhongshan Urology Hospital240
已完成
4 期
Can Low Molecular Weight Heparin During Pregnancy With Intrauterine Growth Restriction Increase Birth Weight?Fetal Growth RetardationNCT01390051University of Aarhus50
尚未招募
4 期
A study to determine effectiveness of Low Molecular Weight Heparin in reduction ofseverity of Acute PancreatitisCTRI/2022/12/048036Jawaharlal Institute of Postgraduate Medical Education and Research
进行中（未招募）
1 期
Impact of the use of low molecular weight heparins (LMWH), at prophylactic versus intermediate doses, on SARS-CoV2 infection (COVID-19)COVID-19EUCTR2020-001891-14-ESFundación Neumosur140