Deep Learning-Based Multidimensional Body Composition Mapping for Predicting Clinical Outcomes in Hepatocellular Carcinoma Patients Undergoing TACE
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- OS
研究概览
简要总结
Hepatocellular carcinoma (HCC) is a common liver cancer, and many patients cannot receive surgery. For these patients, transarterial chemoembolization (TACE) is an important treatment. However, patients often respond differently to TACE, and it is difficult to predict who will benefit most. This study uses deep learning to automatically analyze routine CT images taken before TACE. By measuring body composition features, such as the size and condition of different abdominal organs and tissues, we aim to better understand patients' overall health status and treatment tolerance. The goal is to develop a prediction model that can help doctors estimate survival and treatment outcomes more accurately. This may assist in making more personalized treatment decisions and improving patient care.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients diagnosed with "Hepatocellular Carcinoma" from January 1, 2018 to May 31, 2024;
- •Age > 18 years old.
排除标准
- •Poor image quality;
- •Loss of follow-up;
- •Presence of another type of malignant tumor other than liver cancer;
- •Incomplete medical records.
结局指标
主要结局
OS
时间窗: After the TACE procedure until May 1, 2025
次要结局
- PFS(After the TACE procedure until May 1, 2025)
研究者
Lian Yang
Archiater
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
