A Retrospective Cohort Study for Main Postoperative Complications After SARS-CoV-2 Infection

Not yet recruiting

• Conditions: Gynecologic Disease; Intestines Cancer; Liver Cancer; Trauma; Fractures, Bone; Pulmonary Cancer

• Registration Number: NCT05781581
• Lead Sponsor: RenJi Hospital

Brief Summary

To explore the relationship between SARS-CoV-2 infection in different time before operation and postoperative main complications (mortality, main pulmonary and cardiovascular complications) 30 days after operation; To determine the best timing of surgery after SARS-CoV-2 infection.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-03
• Study First Submitted: 2023-03-12
• Study First Submitted QC: 2023-03-12
• Last Update Submitted: 2023-03-12
• Study Start: 2023-03-19
• Study First Posted: 2023-03-23
• Last Update Posted: 2023-03-23
• Primary Completion: 2023-08-31
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 50000

Inclusion Criteria

• Age≥18 years;
• Patients undergoing any type of surgery in operating room.

Exclusion Criteria

• Surgery under local anesthesia (without participation of anesthetist)
• Surgery outside the operating room, such as gastrointestinal endoscopy, puncture biopsy, etc
• Patients who cannot determine whether they have had SARS CoV-2 infection before surgery.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
All-cause mortality at 30 days after operation	30 days after surgery	All-cause mortality at 30 days after operation

Secondary Outcome Measures

Name	Time	Method
Main pulmonary complications at 30 days after operation	30 days after surgery	a composite of postoperative pneumonia, acute respiratory distress syndrome (ARDS) and unexpected ventilation
Major Adverse Cardiovascular Events (MACE)	30 days after surgery	a composite of cardiogenic death, myocardial infarction, new-onset heart failure or cardiogenic shock, and cerebrovascular accident (CVA)