AC EFFECT ON OXIDATIVE STRESS AND MUSCLE FUNCTION IN COPD PATIENTS.Efecto de NAC en estrés oxidativo y función muscular en pacientes con EPOC

ZAMBON, S.A.0 个研究点目标入组 0 人开始时间: 2005年9月23日最近更新: 2022年4月19日

适应症

试验速览

暂无简介。

•This study will include 30 male ex-smokers between 18-65 years with stable severe COPD, (FEV1/FVC<70%, FEV1<50% predicted) as defined by the Global Initiative for chronic Obstructive Lung Disease guidelines.
•Informed written consent will be obtained.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•Exclusion criteria will be unstable COPD (i.e., exacerbation in the last 2 months), long-term supplemental oxygen and NAC treatment, neuromuscular disease, cardiac failure, diabetes mellitus, arthritis, phenylcetonuria, vascular disease and alcoholism or with a clinical condition or relevant analytical alterations. None of the patients can take systemic oral steroid medication in the 6 months before the study, and all medication regimens remained unchanged during the study period. Will be excluded supplementation with antioxidants or vitamins.
•Also patients with NAC allergy will be excluded.

发起方

ZAMBON, S.A.