Reduction Of Microvascular Injury Utilizing Sonolysis

Completed

• Conditions: acute coronary syndrome; myocardial infarction; 10011082

• Registration Number: NL-OMON41625
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

* Age > 18 years
* acute onset (< 6 hours)
* diagnosed with STEMI according to the criteria of the ACC
* initial oral informed consent

Exclusion Criteria

* Clinical instability
* Known allergy to ultrasound contrast agents
* Any reason judged by the investigators to hamper inclusion

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>* Echocardiographic and enzymatic infarct size<br /><br>* Microvascular obstruction and haemorrhage on MRI measurements<br /><br>Safety and feasibility of therapeutic option</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>* Other adverse events<br /><br>* Other Serious adverse events<br /><br>* Incidence of Major Adverse Cardiac Events (MACE)<br /><br>Other patient and / or MRI and echocardiographic parameters</p><br>