Clinical study on treating Hashimoto's thyroiditis with soothing liver and relieving depressio

Phase 1

• Conditions: Hashimoto's thyroiditis

• Registration Number: ITMCTR2000003957
• Lead Sponsor: Shanghai Yueyang Integrated Traditional Chinese Medicine and Western Medicine Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Diagnosis of Hashimoto's thyroiditis in accordance with Chinese Guidelines for the Diagnosis and Treatment of Thyroid Diseases;
2. Dialectics of TCM belongs to stagnation of liver 'qi';
3. Aged 18 to 65 years;
4. TG<=5 mmol/L;
5. Subjects had no major organ dysfunction and normal liver, kidney and heart function: aspartate transaminase (AST) and alanine transaminase (ALT)<=3 ULN, Creatinine <=1.5 ULN;
6. Signature of informed consent.

Exclusion Criteria

1. Patients with systolic blood pressure of 160 mmHg, or diastolic blood pressure of 100 mmHg;
2. Patients with hyperthyroidism, hypothyroidism or postoperative hormone supplementation in patients with thyroid neoplasms;
3. Patients with myocardial infarction, heart failure or unstable angina;
4. Persons with a history of stroke;
5. Pregnant or lactating women;
6. Persons with mental illness;
7. Cancer patients;
8. Patients allergic to test drugs or their components.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Tg-ab;

Secondary Outcome Measures

Name	Time	Method
TSH, FT3, FT4, T3, T4;TPO-ab;