Eosinophil Half-life in the Lungs of Asthma patients
Completed
- Conditions
- Asthma1000170810038716
- Registration Number
- NL-OMON41515
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
• Age > 18 and younger than 75 years
• Diagnosis of eosinophil asthma
• Suitable for sputum induction
• >1% sputum eosinophils
Exclusion Criteria
Any infection (eg. HIV, Hepatitis, STDs)
Diabetes
Smoking at present or in the last 12 months and/or a past history of more than 10 pack years
Antibiotic treatment for a respiratory tract infection <4 weeks prior to the study
Proven allergic bronchopulmonary aspergillosis
Auto-immune diseases
exuberant alcohol consumption (for males > 36 glasses per week, for females >24 glasses per week)
Drug use
History of cancer
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Determination of eosinophil lifespans in blood and tissue in EA patients. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Lifespans of other leukocytes in blood and lungs of allergic asthma patients</p><br>