Identification of specific volatile organic compound (VOCs) in exhaled breath to distinguish pancreatic ductal adenocarcinoma, pancreatic cystic neoplasm and patients without pancreatic-lesio

• Conditions: - Alveolar air; Pancreatic ductal adenocarcinomaIntraductal Papillary Mucinous NeoplasmVolatile organic compoundExhaled breath; Pancreatic adenocarcinoma; Intraductal papillary mucinous neoplasm ,IPMN; Volatile organic compound; Exhaled breath

• Registration Number: TCTR20211109002
• Lead Sponsor: The Ratchadapisek Sompoch Endowment Fund

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-11-09
• Study Completion: 2022-09-10
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 144

Inclusion Criteria

PDAC group : 1.Age>= 18 years
2.Confirmed diagnosis of PDAC by imaging and tissue diagnosis
2.1Imaging : CT, MRI, EUS
2.2 Tissue : FNA, cytology, Biopsy

Cystic neoplasm group: 1.Age>= 18 years
2.Confirmed diagnosis of IPMN by imaging : CT, MRI, EUS

No-pancreatic lesion group : 1.Age>= 18 years
(age and sex matched with PDAC)
2.Without any pancreatic lesion confirmed with imaging
3.No history of previous pancreatitis

Exclusion Criteria

Concurrent or previous history of 2nd malignancy
Previous treatment of PDAC
Unable to breath through mouth or nose
Pregnancy
Concurrent active infection

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Volatile organic compound pre-treatment TD-GC/FAIMS

Secondary Outcome Measures

Name	Time	Method
Relationship of Amount of Volatile organic compounds to staging and sizing pre-treatment TD-GC/FAIMS