Comparison of Manual Contouring and Atlas Based Autosegmentation in Patients of Lung Cancer.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- 1) To create a new customised Atlas for Lung cancer patients.
研究概览
简要总结
Radiation has an integral role in all stages of lung cancer. In order to deliver therapeutic doses to the target while also protecting the Organs at Risk (OARs), a proper therapeutic plan must be developed which requires a highly precise Target volumes (TVs) and OARs delineation which can be a challenging task. Contouring is the essential and most important part of Radiotherapy treatment planning. However there is an option of Autosegmentation in various softwares. But it is not validated for lung cancer patients in India. This study will validate the auto segmentation softwares in terms of accuracy, time reduction and its application in clinical practice. The library created can then be outsourced and can be used as reference for other centres.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 20.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •Histologically confirmed Non-small cell lung cancer (NSCLC) patients who are referred for definitive treatment (chemoradiation or SBRT).
- •ECOG 0, 1 or
- •Ability to understand and the willingness to sign and informed consent.
排除标准
- •Patients who has metastatic disease.
- •Patients who has received prior Radiotherapy for lung cancer to thoracic region.
- •Pregnant or lactating females.
结局指标
主要结局
1) To create a new customised Atlas for Lung cancer patients.
时间窗: After completion of treatment.
2)To compare manual contouring with auto segmentation in terms of overall contouring time and accuracy using various evaluation metrics like DICE ratio, Hausdorff distance and Volume ratio.
时间窗: After completion of treatment.
次要结局
- Dosimetric analysis between manually segmented contours and auto segmented contours by evaluating maximum and mean doses received by various Organs at Risk.(After 1 year.)
研究者
Dr Dipti Singh
Postgraduate Institute of Medical Education and Research (PGIMER) Chandigarh, India