KCT0003260终止未知
Combination chemotherapy with pazopanib and ICE in children and adolescents with relapsed/refractory solid tumors
适应症
试验速览
- 阶段
- 未知
- 状态
- 终止
- 入组人数
- 46
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional Study
入排标准
- 年龄范围
- 2(Year) 至 22(Year)（—）
- 性别
- All
入选标准
- •Patients with refractory/relapsed solid tumor (Stable or progressive disease after 1st-line treatment or relapse)
- •Patients previously enrolled to Genomic diagnosis of pediatric tumors by NGS (IRB No. SMC 2015-11-053)
排除标准
- •Patients who had high-dose chemotherapy and autologous stem cell transplantation previously
- •Patients with organ dysfunction as follows (creatinine elevation = 1.5 x upper limit of normal (ULN), ejection fraction <40%, significant arrhythmia or conduction disturbance)
- •Patients who are not eligible to have scheduled treatment due to the other significant impaired organ function
- •Patients with active bleeding
- •Patients who are taking strong CYP3A4 inhibitors, QTc-prolonging drugs, antithrombotic agents, or anti-platelet agents
- •Pregnant or nursing women
- •Patients who can not swallow the pill
研究者
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