A clinical trial to study the effect of a drug (Darbepoetin), on haemoglobin in patients with anaemia of chronic disease due to rheumatoid arthritis
Phase 3
- Conditions
- Health Condition 1: M056- Rheumatoid arthritis with involvement of other organs and systems
- Registration Number
- CTRI/2023/03/050776
- Lead Sponsor
- Army Hospital RR
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Age >18 yrs.
2.RA (defined by EULAR criteria 2010)
3.Anaemia of chronic disease as defined by
4.Haemoglobin <13g/dl in males and <12 g/dl in females
5.Normocytic normochromic or microcytic hypochromic RBCs on peripheral blood smear (PBS)
6.Normal or high serum ferritin ( >50 ng/L)
7.Low/normal TIBC
8.Normal or low transferrin saturation
Exclusion Criteria
1.Concomitant additional factor contributing to anaemia like iron or vitamin deficiency, haemolysis etc.
2.Hypertension
3.Chronic organ failure (kidney, heart, liver, lung)
4.History of thromboembolism
5.Splenomegaly
6.Pregnancy and lactation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method