Stress Echocardiography Versus Coronary Angiography for Left Main Stenosis Detection

Withdrawn

• Conditions: Left Main Coronary Artery Disease; Stenosis
• Interventions: Other: Stress echocardiography

• Registration Number: NCT01620320
• Lead Sponsor: Université de Sherbrooke

Brief Summary

Left main stenosis use to be treated by bypass but with the improvement of angioplasty techniques, an increasing number of patients are submit to left main coronary angioplasty. Consequences of left main intra stent stenosis can be disastrous yet, for the moment, no precise recommendation concerning the follow up of these patients exist. The investigators ought to determine if stress echocardiography can predict left main intra stent stenosis as well (non inferiorly)as control angiography that use to be done.

Detailed Description

All patients of the study will pass coronary angiogram and stress echocardiography (treadmill of dobutamine).

Study Timeline

• Study Start: 2010-07
• Study First Submitted: 2010-07-16
• Study First Submitted QC: 2012-06-14
• Study First Posted: 2012-06-15
• Primary Completion: 2012-07
• Status Verified: 2013-06
• Last Update Submitted: 2013-06-24
• Last Update Posted: 2013-06-26
• Study Completion: 2013-07

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• patients over 18 years old able to give consent and having had left main angioplasty.

Exclusion Criteria

• Bypass on the left anterior descending coronary artery or left circumflex (" protected left main ")
• Treating physician judge that angiography need to be done straightaway
• Follow up elsewhere than the CHUS
• Patient refusal
• Pregnant women
• Stress echo contraindication(Severe high blood pressure or malignant arrhythmia)or condition that limits interpretation (Left bundle branch block or pacemaker rhythm)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Stress echography	Stress echocardiography	Nine to twelve months after their left main angioplasty, patients will go through a stress echo and then the usual control angiography (done routinely in most patient in our center). Patients will act as their own control.

Primary Outcome Measures

Name	Time	Method
Correlation between stress echocardiography results for the detection of left main prosthesis stenosis with coronary angiogram results.	9 to 12 months after left main angioplasty

Trial Locations

Locations (1)

Centre Hospitalier Universitaire de Sherbrooke, departement de cardiologie; 🇨🇦 Sherbrooke, Quebec, Canada