Gut Microbiome Transfer for the Treatment of Crohn’s Disease

Associate Professor Justin O'Sullivan0 个研究点目标入组 20 人开始时间: 2018年9月25日最近更新: 2021年5月24日

适应症

试验速览

暂无简介。

•Donor exclusion criteria:
•- Chronic disease
•- Gastrointestinal disease (including irritable bowel syndrome, coeliac and inflammatory bowel disease)
•- Any transmissible viral, bacterial, or protozoan pathogens
•- Current or past history of malignancy (including gastrointestinal cancer or polyposis)
•- Acute substance abuse (including tobacco, >7 standard alcoholic units/week, recreational drugs)
•- Use of probiotics or antibiotics in the past 6 months
•- Atopic diseases (e.g. asthma, eczema)
•- Chronic pain or chronic fatigue syndromes
•- Overseas travel in previous three months
•- Metabolic syndrome
•- First-degree relative with type 2 diabetes mellitus
•Patient exclusion criteria
•- Bowel complications (including abscess, phlegmon, stricture, obstruction, perforation, fistula, or infection)
•- Requiring or expected to require surgery
•- Major abdominal surgery in the past 3 months
•- Use of antibiotics or probiotics in the past 3 months
•- Acute substance abuse (including tobacco, >7 standard alcoholic units/week, recreational drugs)
•- Chronic hepatitis B, C, or HIV infection
•- Diabetes mellitus, cancer, or systemic lupus
•- Food allergies
•- Allergy to Biscodyl tablets or Glycoprep
•- Swallowing dysfunction or esophageal dysmotility

发起方

Associate Professor Justin O'Sullivan