Assessment of sensitivity of Trans-Esophageal Echocardiography for the measurement of cardiac output as compared to that obtained by thermodilution method by Pulmonary Artery Catheter in patients undergoing off-pump coronary artery bypass surgery
Not Applicable
- Conditions
- Health Condition 1: I259- Chronic ischemic heart disease, unspecified
- Registration Number
- CTRI/2022/05/042808
- Lead Sponsor
- G B Pant hospital GIPMER New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Adult patients undergoing off pump CABG with LVEF less than 50%.
Exclusion Criteria
1.Patients with mitral/aortic valve insufficiency or other significant valve abnormalities
2.Patients in non-sinus rhythm
3.Patients requiring inotropic support/IABP/haemodynamically unstable pre-operatively
4.Patients with right ventricular assist device
5.Patients with esophageal diseases
6.Patients requiring conversion from off pump CABG to on pump CABG
7.Patients with ventricular septal defects (VSD) and right ventricle outflow tract (RVOT) / LVOT obstruction.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Cardiac output by thermodilution method <br/ ><br>2.Cardiac output by trans-esophageal echocardiography at aortic valve level <br/ ><br>Timepoint: T1: Clinical steady state 15minutes after induction of anaesthesia <br/ ><br>T2: After sternal closure
- Secondary Outcome Measures
Name Time Method 1.Hemodynamic monitoring including heart rate, systolic, diastolic and mean arterial pressures and pulmonary artery pressure.Timepoint: Every 60minutes throughout the operative period;2.Complications associated with each techniqueTimepoint: intra-operative and post-operative till patient is discharged from ICU;Clinical outcome assessment: <br/ ><br>a)Total inotropic score <br/ ><br>b)Number of shock if needed <br/ ><br>c)Arrhythmia if noted <br/ ><br>d)Morbidity and mortality after risk adjustment <br/ ><br>Timepoint: Intra-operative and post-operative till patient is discharged from IC