The Effect of Injectable PRF Vs LLL on Orthodontic Tooth Movement

Not Applicable

Active, not recruiting

• Conditions: Root Resorption; Rate of Canine Retraction
• Interventions: Device: Low Level LASER; Procedure: Injectable platelet rich fibrin

• Registration Number: NCT06520761
• Lead Sponsor: Faculty of Dental Medicine for Girls

Brief Summary

The purpose of the present study is to compare the effect of injectable platelet fibrin and Low Level LASER therapy on the rate of upper canine retraction, and on root resorption of the canine

Detailed Description

the study involves two groups the first group received low level laser at the upper right canine, while the upper left canine act as a control. The second group received injectable platelet rich fibrin at the upper right canine, while the upper left canine act as a control. in each group we will compare rate of canine retraction between both sides, and amount of root resorption also we will compare both groups regarding rate of canine retraction and amount of root resorption

Study Timeline

• Study Start: 2022-11-01
• Status Verified: 2023-10
• Study First Submitted: 2024-07-20
• Study First Submitted QC: 2024-07-20
• Last Update Submitted: 2024-07-20
• Study First Posted: 2024-07-25
• Last Update Posted: 2024-07-25
• Primary Completion: 2024-12-01
• Study Completion: 2024-12-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: Female
• Target Recruitment: 20

Inclusion Criteria

1. Patients with age 18 years or older.
2. Presence of all permanent teeth except for the third molar.
3. Presence of malocclusion requiring maxillary first premolar extraction such as (class II division 1 or bimaxillary dentoalveolar protrusion).

Exclusion Criteria

1. Patient with a history of previous orthodontic treatment.
2. Medical problems may interfere with orthodontic treatment.
3. Bad oral hygiene.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Low Level LASER	Low Level LASER	low level laser from diode laser machine is applied around the upper right canine and the upper left canine acts as a control
injectable platelet rich fibrin	Injectable platelet rich fibrin	blood sample is collected from the patient, centrifuged at 700rpm for 3 minutes then the resulted injectable platelet rich fibrin is injected around the upper right canine while the upper left canine act as a control

Primary Outcome Measures

Name	Time	Method
Rate of canine retraction	4 month	measure the rate of distal movement of the upper canine

Secondary Outcome Measures

Name	Time	Method
Root resorption of upper canine	4 month	measure root resorption of upper canine

Trial Locations

Locations (1)

Faculty of Dental Medicine for Girls Al Azhar university; 🇪🇬 Cairo, Naser City, Egypt