The Third-trimester Placental Thickness and Pregnancy Outcomes in Placenta Previa Women
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 140
- 试验地点
- 1
- 主要终点
- number of women with placenta accreta
研究概览
简要总结
Placenta previa is the placenta overlying the cervical os. Placenta previa is about 1 in 200 pregnancies. The risk factors are the increasing rate of cesarean section and previous uterine surgery. Placenta previa is associated with many adverse complications; the most serious one is related to maternal hemorrhage. The diagnosis of placenta previa is done by trans-abdominal and trans-vaginal ultrasonography, which can document the placental edge's relationship to the internal os. Placenta accreta spectrum disorder is defined when trophoblastic invades the myometrium. The Placenta accreta spectrum can be categorized as: placenta accreta, placenta increta, and placenta percreta.
The clinical utility of placental thickness is an area of ongoing research in placenta previa. Prior studies have demonstrated an association between mid-trimester placental thickness and placenta accreta spectrum. Despite the presence of many studies in characterizing placental thickness, most studies have focused primarily on the placental accreta spectrum lacking information about other fetal and maternal complications. Symptomatic (bleeding) placenta previa is associated with increased maternal and neonatal morbidity and mortality. In addition; the mechanism that involves bleeding is unclear. It is usually related to uterine contractions, cervical effacement, and dilation leading to separation of the placenta from the underlying decidua.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 35 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Pregnant women from 32-34 weeks.
- •Pregnant women with singleton pregnancy.
- •Women with placenta previa.
- •Placenta previa with minimal vaginal bleeding or haven't any vaginal bleeding.
- •Women without any medical disorders.
- •Women should be living in a nearby area to make follow-up and early transportation is reasonably possible.
排除标准
- •Women with severe bleeding necessitate immediate delivery.
- •Women with confirmed fetal malformation.
- •If associated with abruptio placentae.
- •Women who will refuse to participate.
研究组 & 干预措施
Normal placental thickness women
干预措施: ultrasound (Other)
High placental thickness women
干预措施: ultrasound (Other)
结局指标
主要结局
number of women with placenta accreta
时间窗: 3 weeks
次要结局
未报告次要终点
研究者
Mohammed Khairy Ali
Assistant Professor
Assiut University
