NCT01395602已完成1 期
Randomized Controlled Pilot Study of the Effect of Cabergoline on Body Weight and Glucose Tolerance in Healthy Obese Adults
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- body weight
研究概览
简要总结
The aim of this study is to determine the efficacy of cabergoline, a long-acting dopamine receptor agonist, on body weight and blood glucose in healthy obese adults.
This is a randomized double-blind placebo controlled study. Twenty subjects each will be randomly assigned either placebo or cabergoline for 16 weeks.
The effect of treatment on body weight and blood glucose and insulin levels will be compared in the treatment versus the placebo arm.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 18 - 55 years
- •BMI 30 -40
排除标准
- •diabetes,
- •clinically significant medical condition,
- •use of medications that effect blood glucose or body weight
研究组 & 干预措施
placebo
Placebo Comparator
placebo pill
干预措施: placebo (Other)
cabergoline
Active Comparator
cabergoline pill
干预措施: Cabergoline (Drug)
结局指标
主要结局
body weight
时间窗: 16 weeks
次要结局
- glucose(16 weeks)
研究者
Judith Korner
Associate Professor of Medicine
Columbia University
研究点 (1)
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