A Multidimensional Behavioral Intervention for Those at Risk for Alzheimer's Dementia
- Conditions
- Subjective Cognitive ConcernsBrain Health ActivitiesFunctional AgingCompensation Strategies
- Interventions
- Behavioral: Intervention
- Registration Number
- NCT03549078
- Lead Sponsor
- University of California, Davis
- Brief Summary
This intervention is designed to promote enhanced use of compensation strategies including calendar and task list use, and organization systems, as well as increased engagement with brain health activities including physical exercise, cognitive activities, and stress reduction.
- Detailed Description
The purpose of this study is to test the feasibility and efficacy of a 10-week multi-dimensional intervention for older adults with subjective cognitive concerns (SCC). The goal of this intervention is to enhance compensation skills related to everyday executive and everyday memory functions through training in the systematic use of a calendar system, goal setting and task list system, and organizational strategies within the context of the individual's daily life. This multidimensional intervention program also targets engagement in healthy lifestyle activities (physical exercise, intellectual stimulation, positive emotional functioning) to further promote brain health and functional resilience. Importantly, both treatment components work synergistically as the use of compensation strategies assists in building healthy activities into daily routines (e.g., scheduling exercise into one's calendar and putting it on a task list).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 69
- A positive complaint in response to two questions ('Do you feel like your memory or other aspects of thinking are becoming worse?'; 'Does this worry you?')
- normal cognitive performance corrected for age and education on a global measure of cognitive functioning
- independent in all activities of daily living.
- English speaking;
- Available informant to complete surveys;
- Ambulatory
- Known neurological condition;
- Severe psychiatric illness (e.g., current depression).
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Intervention Intervention Participants will complete an initial assessment within 2 weeks prior to starting the course or during the first class. The course will include 10 sessions conducted on a weekly basis. Following completion of the course, participants will again complete another assessment during the last class or within 2 weeks of course completion. Participants may be invited to complete assessments at 3- and 6-months following course completion.
- Primary Outcome Measures
Name Time Method Everyday Compensation Questionnaire Change from baseline to immediately post-intervention and through 6 month follow up a 54-item self-report questionnaire that asks participants how often they engage in a variety of activities that help them stay cognitively and physically active.
Everyday Cognition Change from baseline to immediately post-intervention and through 6 month follow up self-rated questionnaire of cognitively-based everyday abilities. The ECog comprises of 39 items on which the participant's current level of everyday functioning is compared to 10 years earlier. Items are rated on a four-point scale: 1= better or no change compared to 10 years earlier; 4= consistently much worse. Higher scores indicate greater functional limitations
- Secondary Outcome Measures
Name Time Method GRIT Measured at baseline, immediately after intervention, and 3 and 6 month follow up visits an 8-item questionnaire assessing consistency of interest and perseverance of effort on a five-point scale: 1 = not at all like me, 5 = very much like me.
Beck Anxiety Inventory Measured at baseline, immediately after intervention, and 3 and 6 month follow up visits Measures anxiety symptomatology
Executive function task Measured at baseline, immediately after intervention, and 3 and 6 month follow up visits measures executive function
List learning task Measured at baseline, immediately after intervention, and 3 and 6 month follow up visits measures learning and memory
psychomotor speed task Measured at baseline, immediately after intervention, and 3 and 6 month follow up visits measures psychomotor speed function
Beck Depression Inventory Measured at baseline, immediately after intervention, and 3 and 6 month follow up visits Measures depressive symptomatology
Trial Locations
- Locations (1)
University of California Davis
🇺🇸Sacramento, California, United States