Prospective trial of esophagogastroscopy versus thoracic computed tomography in prediction of upper gastrointestinal tract stricture after caustic ingestio
- Conditions
- Caustic ingestionBurns, Caustics, Caustic ingestion, Chemical, Computed Tomography, Corrosive injury, Endoscopy, Esophageal injury, Esophageal stricture, Esophagogastroscopy, Gastric outlet obstruction
- Registration Number
- TCTR20240320009
- Lead Sponsor
- Faculty of Medicine, Thammasat University
- Brief Summary
Computed tomography (CT) is a viable alternative to endoscopy with several benefits, including a shorter timeframe from ingestion to the procedure, mitigating endoscopic complications such as perforation, bleeding, or aspiration, avoiding unnecessary surgical interventions, and providing ease of accessibility in developing countries where there is a shortage of digestive surgeons.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 23
Patients who have experienced caustic ingestion within 24 hour
1. Previous surgery of esophagus or stomach, 2. Patients with esophageal or gastric cancer, 3. Patients with hemodynamic instability and not respond to adequate resuscitation, 4. Physical examination suggests perforated viscus or airway (eg., subcutaneous emphysema), 5. Plain films reveal perforated viscus or airway
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The ability of endoscopy and CT scanning in predicting caustic strictures 3 weeks following caustic ingestion AUROC (Area Under the Receiver Operating Characteristic) curve
- Secondary Outcome Measures
Name Time Method Sensitivity, specificity, positive predictive value, negative predictive value of endoscopy and CT scanning in predicting caustic strictures. 3 weeks following caustic ingestion Sensitivity, specificity, positive predictive value, negative predictive value