Effects of a single and long-term consumption of citrus fibre on glucose metabolism in humans
- Conditions
- Healthy subjects with a metabolic risk profile (waist circumference >88 cm in women and >102 cm in men)
- Registration Number
- DRKS00027430
- Lead Sponsor
- Technische Universität München Lehrstuhl für Ernährungsmedizin
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 17
Providing written informed consent
- 35-67 years old
- Waist circumference >88 cm (women) and >102 cm (men)
- Not providing written informed consent,
- Parallel participation in another interventional study
- Chronic diseases: Diabetes mellitus, untreated hypertension (>160/95 mmHg), untreated hormonal diseases (e.g. hyperthyroidism, hypothyroidism), chronic liver diseases (e.g. HBV, HCV), autoimmune diseases (rheumatism, ulcerative colitis, Crohn's disease), chronic infections (e.g. HIV), cardiovascular disease, tumor disease, diverticulosis,
- Acute infectious diseases,
- Allergy or sensitivity to the study products,
- Current dietary fibre supplementation
- Pregnancy and breastfeeding,
- Having donated blood in the prior 3 months
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcomes of the study are following blood-glucose related parameters:<br><br>Intervention days:<br><br>- peak glucose value<br>- time to peak<br>- glucose AUC<br>- shape of the glucose curve<br><br>14-day-long intervention phases:<br><br>- mean glucose values (24 hours, during the day, at night)<br>- mean fasting glucose values<br>- the amount of time in the target blood sugar (Time in range)<br>- glucose variability
- Secondary Outcome Measures
Name Time Method