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临床试验/NCT06759220
NCT06759220尚未招募不适用

Hystrolaparosciopic Findings in Infertile Women with Secondary Infertility

Assiut University1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2025年9月21日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
150
试验地点
1
主要终点
Primary (main): rate and pattern of abnormal laparoscopic and hysteroscopic findings in infertile women with previous uterine surgery

研究概览

简要总结

  1. to determine the rate and pattern of abnormal laparoscopic finding among the infertile women with history of previous uterine surgery.
  2. To detemine the rate and pattern of abnormal hysteroscopic finding among infertile women with with history of previous uterine sergery
  3. to evaluate the value of doing combined laparoscopy and hysteroscopy in infertile women with with history of previous uterine surgery.
  4. To determine possible risk factors of pelvic adhesions detected during laparoscopy.
  5. To determine possible risk factors causing cs niche.

详细描述

nfertility(1), which refers to the inability of a couple to conceive after one year of regular unprotected sexual intercourse, is the commonest indication for gynacological consultation. primary infertility - where someone who's never conceived a child in the past. secondary infertility(2) - where someone has had 1 or more pregnancies in the past, but is having difficulty conceiving again.there are many causes for infertility. (3)uterine causes as uterine fibroids or malformations.tubal factors as tuboperitoneal adhesions,unilateral or bilateral proximal occlusion unilateral or bilateral hydrosalpinx or pyosalpinx.Ovarian factors ovarian cyst,polycystic ovaries.pelvic causes as adhesions ,endometriosis and miscellaneous. laparoscopy can be used as the gold standard diagnostic tool which allows direct visualization of all pelvic organs. It also helps in detailed assessment of fallopian tubes. The advantage behind using laparoscopy is that the treatment of certain conditions such as tubal obstruction, endometriosis, and pelvic adhesions can be done at the same time during diagnosis. If needed, laparoscopic chromopertubation can also be done for tubal patency during the same sitting. (4)Hysteroscopy is the direct visualization of the uterine cavity using an endoscope. Uterine cavity evaluation is very much needed to do achieve total infertility workup. Uterine abnormalities are present among 10-15% of couples who seek treatment of infertility. For evaluation of endometrial factors,(5) hysteroscopy considered to be a gold standard. Diagnostic h hysteroscopy can detect uterine anomalies which remain undetected in USG and other routine investigations.

Many studies reported the occurrence of pelvic adhesions following cesarean section with its related consequences.

pelvic adhesions may affect both reproductive system anatomy and function, causing various associated conditions. Pelvic adhesions may cause secondary infertility, which might be due to dyspareunia, disturbing tubo-ovarian relationship, or disturbing peristaltic movement of fallopian tube.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
20 Years 至 35 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • All women between20 to 35 yrs old with secondary infertiliy for 2 years
  • Women with previous uterine surgery

排除标准

  • Female with major medical illness(Uncontrolled daibetes, cardiac diseases, uncontrolled thyroid disorders)
  • Abnormal semen parameter of the husband.

结局指标

主要结局

Primary (main): rate and pattern of abnormal laparoscopic and hysteroscopic findings in infertile women with previous uterine surgery

时间窗: Baseline

Primary (main): rate and pattern of abnormal laparoscopic and hysteroscopic findings in infertile women with previous uterine surgery

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dalia Ali Ramadan

Dalia Ali Ramadan

Assiut University

研究点 (1)

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