Hystrolaparoscopic Findings in Infertile Women with Previous Uterine Surgery

Not yet recruiting

• Conditions: Hystrolaparoscopic Findings in Infertile Women with Previous Uterine Surgeries

• Registration Number: NCT06759220
• Lead Sponsor: Assiut University

Brief Summary

1. to determine the rate and pattern of abnormal laparoscopic finding among the infertile women with history of previous uterine surgery.

2. To detemine the rate and pattern of abnormal hysteroscopic finding among infertile women with with history of previous uterine sergery

3. to evaluate the value of doing combined laparoscopy and hysteroscopy in infertile women with with history of previous uterine surgery.

4. To determine possible risk factors of pelvic adhesions detected during laparoscopy.

5. To determine possible risk factors causing cs niche.

Detailed Description

nfertility(1), which refers to the inability of a couple to conceive after one year of regular unprotected sexual intercourse, is the commonest indication for gynacological consultation. primary infertility - where someone who's never conceived a child in the past. secondary infertility(2) - where someone has had 1 or more pregnancies in the past, but is having difficulty conceiving again.there are many causes for infertility. (3)uterine causes as uterine fibroids or malformations.tubal factors as tuboperitoneal adhesions,unilateral or bilateral proximal occlusion unilateral or bilateral hydrosalpinx or pyosalpinx.Ovarian factors ovarian cyst,polycystic ovaries.pelvic causes as adhesions ,endometriosis and miscellaneous. laparoscopy can be used as the gold standard diagnostic tool which allows direct visualization of all pelvic organs. It also helps in detailed assessment of fallopian tubes. The advantage behind using laparoscopy is that the treatment of certain conditions such as tubal obstruction, endometriosis, and pelvic adhesions can be done at the same time during diagnosis. If needed, laparoscopic chromopertubation can also be done for tubal patency during the same sitting. (4)Hysteroscopy is the direct visualization of the uterine cavity using an endoscope. Uterine cavity evaluation is very much needed to do achieve total infertility workup. Uterine abnormalities are present among 10-15% of couples who seek treatment of infertility. For evaluation of endometrial factors,(5) hysteroscopy considered to be a gold standard. Diagnostic h hysteroscopy can detect uterine anomalies which remain undetected in USG and other routine investigations.

Many studies reported the occurrence of pelvic adhesions following cesarean section with its related consequences.

pelvic adhesions may affect both reproductive system anatomy and function, causing various associated conditions. Pelvic adhesions may cause secondary infertility, which might be due to dyspareunia, disturbing tubo-ovarian relationship, or disturbing peristaltic movement of fallopian tube.

Study Timeline

• Status Verified: 2024-09
• Study First Submitted: 2024-12-30
• Study First Submitted QC: 2024-12-30
• Last Update Submitted: 2024-12-30
• Study First Posted: 2025-01-06
• Last Update Posted: 2025-01-06
• Study Start: 2025-09-21
• Primary Completion: 2027-03-21
• Study Completion: 2028-09-21

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: Female
• Target Recruitment: 150

Inclusion Criteria

• All women between20 to 35 yrs old with secondary infertiliy for 2 years
• Women with previous uterine surgery

Exclusion Criteria

• Female with major medical illness(Uncontrolled daibetes, cardiac diseases, uncontrolled thyroid disorders)
• Abnormal semen parameter of the husband.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary (main): rate and pattern of abnormal laparoscopic and hysteroscopic findings in infertile women with previous uterine surgery	Baseline	Primary (main): rate and pattern of abnormal laparoscopic and hysteroscopic findings in infertile women with previous uterine surgery

Trial Locations

Locations (1)

Women's health hospital Assiut University; 🇪🇬 Assiut, Egypt