Effect of laser therapy and strengthening exercises on hand function in patients of carpal tunnel syndrome with rheumatoid arthritis
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- NPRS, DAS-28, NCV, FSS, SSS and
研究概览
简要总结
Carpal tunnel syndrome (CTS) is an entrapment neuropathy in which median nerve is
compressed or squeezed at the wrist level in the carpal tunnel.
Recently, trials of laser therapy without any side effects have demonstrated benefits on clinical
and electrophysiological parameters. Laser therapy, also called as photobiomodulation, can
reduce pain, inflammation, swelling and synovitis. Studies also indicated tissue remodeling
and regeneration effects of laser therapy. Photons produced by laser therapy are absorbed in
the cells which increased ATP production, induce cellular events such as DNA synthesis and
replication, cell proliferation, cell differentiation and protein synthesis. Low-intensity lasers
has non-thermal and non-invasive effect on biological systems. The dexterity and
functionality of the hands improved through hand and wrist stretching and strengthening
exercises.
Although there are many studies which have reported efficacy of laser therapy on carpal
tunnel syndrome. But only a few studies have studied the effect of laser therapy on patients of
CTS with RA. To our knowledge, no study has observed the effect of laser therapy with
strengthening exercises in patients of CTS with RA till now.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 30.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients diagnosed for RA with CTS by physician 2) Both male and female patients of age ≥ 30 years.
排除标准
- •Underlying metabolic disorder such as diabetes mellitus and thyroid disorders, acromegaly 2) Cervical radiculopathy, Peripheral neuropathies 3) Pregnancy 4) Intractable pain due to CTS 5) History of :Steroid injection, laser therapy at wrist in previous 3 months, carpal tunnel wrist surgery, recent wrist trauma and fractures.
结局指标
主要结局
NPRS, DAS-28, NCV, FSS, SSS and
时间窗: Day 0 and Day 42
dynamometer
时间窗: Day 0 and Day 42
次要结局
- Grip strength, symptoms severity,hand function,nerve conduction, disease activation of RA, intensity of pain(Day 0 and Day 42)
研究者
Zafar Mohammad
College of Physiotherapy, Pt. B. D. Sharma University of Health Sciences, PGIMS, Rohtak