Local and Systemic Inflammatory Bone Alterations Related to Dental Implant Survival.
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 192
- 试验地点
- 1
- 主要终点
- Difference in the prevalence of implant failure and peri-implantitis between patients presenting with local and/or systemic alterations involving the bone.
研究概览
简要总结
Introduction: Dental implants offer a durable, aesthetic, and functional option for tooth replacement. However, they are not immune to failure. Current literature has highlighted the importance of systemic factors (such as vitamin D deficiency, osteoporosis and hypercolesterolemia) and local factors (such as the presence of nearby periapical infections or implant placement in sites with a history of endodontic failure) that affect bone health.
Hypothesis: Bone alterations-whether systemic or local-represent a risk factor for implant failure and peri-implantitis.
Objectives: To analyze implant failure and marginal bone loss in patients with local and/or systemic bone alterations compared to patients without such conditions.
Methods: Implant failures occurring in patients treated within the Master's Program in Oral Medicine, Surgery, and Implantology at the University of Barcelona (MCIO-UB) over the last 10 years will be analyzed and correlated with bone factors (local and systemic) recorded in their medical histories. Cases lacking the radiographic and clinical data necessary to conduct the study will be excluded.
Population: A total of 3,500 implants have been placed, with failure rates ranging from 4% to 8% depending on the techniques used; consequently, the study sample will consist of 192 implants. Cohorts of successful implants will be established by matching patients of the same sex and within a ±5-year age range who did not experience implant failure.
详细描述
This is a retrospective cohort study, in which it is intended to reveal the relationship between local and systemic bone conditions and their paper in dental implants failure and peri-implant bone loss.
The sample will be selected from patients who have undergone implant placement at the University of Barcelona Dental Hospital (HOUB).
The inclusion criteria will be:
- Patients over 18 years of age
- Patients with implants placed within the last 10 years
- Patients with accessible complete medical and dental records
- Patients with documented implant follow-up via periapical radiographs and/or OPG
- Patients with documented pre-implant tooth status
- Patients with blood test results available from the 6 months prior to or following implant placement
- Implants lost due to peri-implant pathology causing bone resorption
- Implants which have shown osseointegration success during the last 10 years
Patients will be excluded if they fail to meet the inclusion criteria
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients over 18 years of age
- •Patients with implants placed within the last 10 years
- •Patients with access to complete medical and dental records
- •Patients with documented implant progression via periapical radiographs and/or OPG
- •Patients with documented pre-implant tooth status
- •Patients with blood test results from the 6 months prior to or following implant placement
- •Implants lost due to peri-implant pathology causing bone resorption
排除标准
- •Those patients who does not meet inclusion criteria
研究组 & 干预措施
Implant Success
patients in which dental implants had not been lost since the positioning
Implant Failure
patients in which dental implants had been lost since the positioning
结局指标
主要结局
Difference in the prevalence of implant failure and peri-implantitis between patients presenting with local and/or systemic alterations involving the bone.
时间窗: 2013-2026
To see the differences of prevalences of all those factors affecting implants in the patients who present a success or failure of dental implants. The measurements that will be used will be all those taking into account local and systemic bone conditions and the final outcome of the implant: failure, bone loss or success.
次要结局
- Relationship of osteoporosis and implant failure(2013-2026)
- Relationship of vitamine D levels and implant failure(2013-2026)
- Relationship between dental implant failure and dental failure(2013-2026)
- Relationship between the presence of an adjacent endodontically treated tooth and implant failure(2013-2026)
- Paper of dental prosthesis in implant failure(2013-2026)
研究者
F. Javier Parra Moreno
Associate professor of the department of Oral Medicine of the University of Barcelona
University of Barcelona