跳至主要内容
临床试验/NCT02233010
NCT02233010已完成不适用

Usefulness of Neutrophil Gelatinase-associated Lipocalin(NGAL) to Confirm Acute Kidney Function Decrease of the Patients Who Had Non-cardiac Surgery

Inje University0 个研究点目标入组 43 人开始时间: 2014年2月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
43
主要终点
serum NGAL level

研究概览

简要总结

Although post-op renal function decrease is determined by serum creatinine, serum creatinine has disadvantages that it increases a long time after renal function decrease and it has various increasing time based on the level of renal function. Neutrophil Gelatinase-associated Lipocalin (NGAL's) usefulness as an evidence for acute kidney damage occurring from post-op cardiac surgery, being critical patients and contrast medium use is already proven.

But NGAL's usefulness for renal function after non-cardiac surgery is not proven and especially, NGAL's usefulness for renal injury after non-cardiac surgery in chronic renal disease patients is not proven.Therefore, the investigators will study about renal function decrease after non-cardiac surgery with NGAL and serum creatinine.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 79 Years(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •43 patients who had non-cardiac surgery in Seoul Paik Hospital.

排除标准

  • •have viral hepatitis and Aspartate aminotransferase, Alanine aminotransferase > 2 time of normal level
  • •severe lung disease
  • •severe heart failure ( Ejection Fraction < 40% )
  • •pregnancy

结局指标

主要结局

serum NGAL level

时间窗: up to post operation 12 hours

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Hoseok Koo

Hoseok Koo

Inje University

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