Fertility Decision and Outcomes in Young Women With Breast Cancer
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 300
- 试验地点
- 3
- 主要终点
- Childbearing after breast cancer diagnosis
研究概览
简要总结
This observational study is to learn about the fertility outcomes and decision after breast cancer diagnosis, and the current status of fertility consultation and decision support in young women diagnosed with breast cancer in China.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Female breast cancer patients, aged 18-40 years at diagnosis.
- •Treated at the three participating hospitals between 1 January 2013 and 31 December
- •Complete clinical documentation available in the electronic medical record system.
- •Had no child before cancer diagnosis.
排除标准
- •Prior reproductive compromise (surgical or diagnostic infertility or pre-existing infertility factors) before cancer diagnosis.
- •Presented with de novo stage IV (metastatic) disease.
- •Had a history of other malignancies.
- •Patients who refuse to participate or cannot be contacted for follow-up.
研究组 & 干预措施
Control Group (Childbearing after diagnosis)
Patients diagnosed with breast cancer who had no live birth prior to diagnosis but had at least one live birth after diagnosis.
干预措施: No intervention (observational study) (Other)
Case Group (No childbearing after diagnosis)
Patients diagnosed with breast cancer who had no live birth prior to diagnosis but had no live birth after diagnosis.
干预措施: No intervention (observational study) (Other)
结局指标
主要结局
Childbearing after breast cancer diagnosis
时间窗: Up to 2026
We will follow up with patients who had not given birth before their cancer diagnosis, to establish whether they had given birth by the end of follow-up. It will be assessed by patient self-report during follow-up and available medical records. The outcome will be recorded as a binary variable (yes/no).
次要结局
- Fertility preservation measures uptake(up to 2026)
- Multidisciplinary collaboration involvement(up to 2026)