ong-term cellular memory immunity against Bordetella pertussis and other components of the DTP-IPV-Hib vaccine in Dutch children: comparison of a whole cell vaccine (WCV) with an acellular vaccine (ACV)

Not Applicable

Completed

• Conditions: Whooping cough/ Bordetella pertussis infection; Infections and Infestations; Whooping cough

• Registration Number: ISRCTN65428640
• Lead Sponsor: ational Institute for Public Health and the Environment (RIVM) (The Netherlands)

Brief Summary

2013 results in: https://www.ncbi.nlm.nih.gov/pubmed/23825195 (added 04/07/2019)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2007-12-18
• Study Start: 2008-11-07
• Last Update Posted: 29 July 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 338

Inclusion Criteria

1. Both male and female children, aged 3 to 9 years old
2. Infants in good general health (eligible) who have been vaccinated according to the Dutch national vaccination programme
3. Provision of written informed consent by both parents and legal representatives

Exclusion Criteria

1. Present evidence of serious disease(s) demanding immunosuppressive medical treatment, such as corticosteroids, that might interfere with the results of the study within 3 months
2. Any known primary or secondary immunodeficiency
3. Vaccination with any other vaccine than those used in the National Immunisation Programme (Rijks Vaccinatie Programma [RVP]) within a month before the blood sampling

Study & Design

• Study Type: Observational
• Study Design: Not specified