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Clinical Trials/NCT03392519
NCT03392519
Completed
Not Applicable

Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging Study About Reorganization and Recovery Mechanism of Brain Neural Network for Chronic Stroke Patients

Samsung Medical Center1 site in 1 country59 target enrollmentAugust 18, 2015
ConditionsChronic Stroke

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Stroke
Sponsor
Samsung Medical Center
Enrollment
59
Locations
1
Primary Endpoint
Correlation coefficient between strength of connection and the Fugl-Meyer Assessment score
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

In chronic stroke patients, brain network reorganization and recovery mechanism are investigated after stroke onset using functional MRI and diffusion tensor imaging analyses.

Registry
clinicaltrials.gov
Start Date
August 18, 2015
End Date
July 17, 2020
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • more than 3 months post-stroke
  • ischemic or hemorrhagic stroke
  • a person who understands the experiment and has a willingness to participate and signs the agreement

Exclusion Criteria

  • User of artificial heartbeat
  • Patients with claustrophobia
  • Patients with metal implants
  • Patients who are contraindicated for other common MRI

Outcomes

Primary Outcomes

Correlation coefficient between strength of connection and the Fugl-Meyer Assessment score

Time Frame: Through study completion, an average of 1 year

Strength of connection is obtained by calculating a correlation coefficient between time courses of both regions in fMRI data.

Correlation coefficient between the FA value of a tract and the Fugl-Meyer Assessment score

Time Frame: Through study completion, an average of 1 year

FA value is obtained by assessing a diffusion anisotropy of a specific tract in DTI data.

Study Sites (1)

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