Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging Study About Reorganization and Recovery Mechanism of Brain Neural Network for Chronic Stroke Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Stroke
- Sponsor
- Samsung Medical Center
- Enrollment
- 59
- Locations
- 1
- Primary Endpoint
- Correlation coefficient between strength of connection and the Fugl-Meyer Assessment score
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
In chronic stroke patients, brain network reorganization and recovery mechanism are investigated after stroke onset using functional MRI and diffusion tensor imaging analyses.
Investigators
Eligibility Criteria
Inclusion Criteria
- •more than 3 months post-stroke
- •ischemic or hemorrhagic stroke
- •a person who understands the experiment and has a willingness to participate and signs the agreement
Exclusion Criteria
- •User of artificial heartbeat
- •Patients with claustrophobia
- •Patients with metal implants
- •Patients who are contraindicated for other common MRI
Outcomes
Primary Outcomes
Correlation coefficient between strength of connection and the Fugl-Meyer Assessment score
Time Frame: Through study completion, an average of 1 year
Strength of connection is obtained by calculating a correlation coefficient between time courses of both regions in fMRI data.
Correlation coefficient between the FA value of a tract and the Fugl-Meyer Assessment score
Time Frame: Through study completion, an average of 1 year
FA value is obtained by assessing a diffusion anisotropy of a specific tract in DTI data.