Brain Imaging Study of Brain Plasticity in Chronic Stroke Patients

Completed

• Conditions: Chronic Stroke
• Interventions: Other: Chronic stroke

• Registration Number: NCT03392519
• Lead Sponsor: Samsung Medical Center

Brief Summary

In chronic stroke patients, brain network reorganization and recovery mechanism are investigated after stroke onset using functional MRI and diffusion tensor imaging analyses.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2015-08-18
• Study First Submitted: 2017-12-25
• Study First Submitted QC: 2018-01-02
• Study First Posted: 2018-01-08
• Status Verified: 2019-09
• Primary Completion: 2020-06-30
• Study Completion: 2020-07-17
• Last Update Submitted: 2023-03-07
• Last Update Posted: 2023-03-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 59

Inclusion Criteria

• more than 3 months post-stroke
• ischemic or hemorrhagic stroke
• a person who understands the experiment and has a willingness to participate and signs the agreement

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Exclusion Criteria

• User of artificial heartbeat
• Patients with claustrophobia
• Patients with metal implants
• Patients who are contraindicated for other common MRI

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Chronic stroke	Chronic stroke	More than 3 months post-stroke Ischemic or hemorrhagic stroke

Primary Outcome Measures

Name	Time	Method
Correlation coefficient between strength of connection and the Fugl-Meyer Assessment score	Through study completion, an average of 1 year	Strength of connection is obtained by calculating a correlation coefficient between time courses of both regions in fMRI data.
Correlation coefficient between the FA value of a tract and the Fugl-Meyer Assessment score	Through study completion, an average of 1 year	FA value is obtained by assessing a diffusion anisotropy of a specific tract in DTI data.

Trial Locations

Locations (1)

Samsung Medical Center; 🇰🇷 Seoul, Korea, Republic of