The impact of osteoporosis on jaw bones

Not Applicable

Completed

• Conditions: Osteoporosis, residual ridge resorption, quality of the jawbones; Musculoskeletal Diseases

• Registration Number: ISRCTN10873942
• Lead Sponsor: Riga Stradins University

Brief Summary

2022 Results article in https://pubmed.ncbi.nlm.nih.gov/34535433/ (added 04/10/2022) 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/36661554/ (added 20/12/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-11-05
• Study Completion: 2021-08-31
• Last Update Posted: 8 January 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 127

Inclusion Criteria

The study will include female patients of Riga Stradinš University Institute of Stomatology who:
1. Undergo CBCT (cone beam computed tomography) diagnostics due to other indications
2. Have menopause
3. Age 55-95 years
4. Agrees to participate in the study
5. At least 5 years edentulous
6. At least 3 years wearing complete dentures
7. Receive prosthetic treatment in Institute of Stomatology (complete dentures)

Exclusion Criteria

1. Patients with diseases and conditions leading to the secondary osteoporosis (kidney disease, hyperparathyroidism, Cushing syndrome, thyrotoxicosis, rheumatoid arthritis, organ transplantation, diabetes mellitus)
2. Women with early menopause (before age 45) or surgical menopause
3. Patients who use or have used a year prior to the study medications affecting bone metabolism (glucocorticoids, bisphosphonates, strontium ranelate, selective oestrogen receptor modulators, HRT, calcitonin, active metabolite of vitamin D, teriparatide, etc.) except those who use calcium less than 1000 mg or vitamin D less than 800 IU per day
4. Smokers
5. Excessive alcohol abusers (more than 14 alcohol units per week)

Study & Design

• Study Type: Observational
• Study Design: Not specified