Effect of antiinflammatory eye drops (topical nepafenac 0.3%) on retinal thickness (central macular thickness) after cataract surgery in patients with diabetes: A randomized controlled trial

Not yet recruiting

• Conditions: Type 2 diabetes mellitus with ophthalmic complications,

• Registration Number: CTRI/2023/03/050650
• Lead Sponsor: pondicherry institute of medical sciences

Brief Summary

**Title of the dissertation:** Effect of perioperative topical nepafenac 0.3% on central macular     thickness after cataract surgery in patients with diabetes: A randomized controlled trial

**Primary objectives:** To determine the effect of perioperative nepafenac 0.3% on central macular thickness after uneventful cataract surgery in diabetes**Secondary objectives:** To determine the association of the effect of nepafenac (0.3%) with post cataract surgery visual acuity**.**

Detailed Description

Not available

Study Timeline

• Study Start: 2023-03-16
• Last Update Posted: 2023-07-03

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 136

Inclusion Criteria

All diabetic patients in the age group 40yrs and above, will be undergoing routine cataract surgery.

Exclusion Criteria

• •Preexisting macular diseases/ macular oedema •Recent intraocular surgery other than cataract surgery for 3 months •Intra operative complications during the surgery •Allergic or hypersensitive to NSAIDS, corticosteroids •Chronic and recurrent inflammatory eye diseases.
• •Use of any eye drops in last three months.
• •Diseases causing macular edema other than diabetes are age related macular degeneration, Retinal venous occlusion, Coats disease, Radiation retinopathy, choroidal tumors and retinitis pigmentosa Other drugs like chloroquine, tamoxifen and interferon can induce macular edema.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To determine the effect of perioperative nepafenac 0.3% on central macular thickness after uneventful cataract surgery in diabetes	Follow up day 1, day-7, day 28

Secondary Outcome Measures

Name	Time	Method
To determine the association of the effect of nepafenac (0.3%) with post cataract surgery visual acuity.	Follow up day 1, day-7, day 28

Trial Locations

Locations (1)

pondicherry institute of medical sciences; 🇮🇳 Pondicherry, PONDICHERRY, India

pondicherry institute of medical sciences

🇮🇳Pondicherry, PONDICHERRY, India

kale satya geethika

Principal investigator

9790198249

geethikakale94@gmail.com