Acute Effect of Passive Joint Mobilization on Joint Motion And Pain Perception in Non-Specific Neck Pain
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 53
- 试验地点
- 1
- 主要终点
- Pain Pressure Threshold
研究概览
简要总结
Aim of present study is investigating the acute effects of passive joint mobilization on pain perception and range of motion. Study protocol includes passive joint mobilization application to study group with neck pain and blood sample collection of study and healthy control group.
详细描述
Our purpose of planning this study is to examine the acute effect of passive joint mobilization application on pain perception and range of motion in women with non-specific neck pain.
The hypotheses we will test for this purpose;
H1- Passive joint mobilization application increases the range of motion of the cervical joint in women with non-specific neck pain.
H2- Passive joint mobilization application increases the pressure pain threshold in women with non-specific neck pain.
H3- Passive joint mobilization increases serum Orexin A and Neurotensin levels in women with non-specific neck pain.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 24 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •For Intervention Group;
- •Having neck pain lasting more than 30 days and being diagnosed with non-specific neck pain
- •Having obtained 14/50 points and above in Neck Disability Index
- •Expressing neck pain at least 34/100 points and above on a Visual Analog Scale
- •Being 20-45 years old and female
- •For Healthy Control Group;
- •Healthy volunteers without a chronic illness and musculoskeletal pain
排除标准
- •Congenital anomalies
- •Previously diagnosed orthopedic diseases related to the spine
- •Pregnancy and having just given birth
- •Within the last 3 months; use of corticosteroids, cytotoxic drugs, or immunosuppressants
- •Liver or kidney failure
- •Acute or chronic infections (including HIV)
- •Serious pathologies (such as cancer, spondylolisthesis, rheumatoid arthritis or ankylosing spondylitis)
- •Symptoms of cervical spinal stenosis (such as incoordination of hands, arms and legs, bowel and bladder incontinence)
- •Radix compression (such as sensory changes, muscle weakness or decreased reflexes)
- •Whiplash or a history of cervical surgery
研究组 & 干预措施
Intervention Group
24 female participants with non-specific neck pain included in the mobilization group will undergo detailed manual cervical examination. In the evaluation, the most painful segment with dysfunction will be selected and mobilization application and algometric measurements will be performed on this segment. Grade 3 Central Posterior-Anterior (CPA) passive joint mobilization with Maitland method will be applied in 3 sets, 30 seconds, to the segment with the detected dysfunction.
干预措施: Passive Cervical Joint Mobilization (Other)
Healthy Control Group
Healthy volunteer participants included in the control group will only be applied an evaluation protocol and blood samples will be taken without any application.
结局指标
主要结局
Pain Pressure Threshold
时间窗: Pain Pressure Threshold assessment will take maximum of 5 minutes.
Pressure Pain Threshold will be measured with the JTech Commander Algometer at the level of the right and left zygapophyseal joint of the dysfunctional cervical segment detected during physical examination. During the evaluation, the participants will be asked to lie in a prone position. By placing the probe of the algometer vertically on the skin, the pressure applied will be gradually increased and the participant will be asked to report at the first moment of pain. The measurement will be made once and the result will be recorded in kilograms.
Cervical Range of Motion
时间窗: Cervical Range of Motion assessment will take maximum of 5 minutes.
Cervical Range of Motion will be assessed by Baselşne Bubble Inclinometer as degree of flexion-extension, rotation and lateral flexion and will be recorded.
Neuropeptide Measurement
时间窗: Blood Sample Collection for Neuropeptide Measurement will take maximum of 5 minutes.
Neuropeptide Measurement will be performed as a result of evaluating the blood samples taken from the participants with the appropriate ELISA kits. Orexin A and Neurotensin levels are planned to be evaluated with Human Orexin A (Competitive EIA) ELISA Kit and Human NTS / NT / Neurotensin (Competitive EIA) ELISA Kit which are specific for these neuropeptides.
次要结局
- Pain Intensity Measurement(Pain Intensity Measurement will take maximum of 1 minute.)
- Neck Disability(Neck Disability measurement will take maximum of 1 minute.)
研究者
Mücahit ÖZTOP
Research Assistant
Pamukkale University