Comparison of penumbra quantification in acute ischemic stroke between MR SWI-DWI mismatch versus MR ASL PWI-DWI mismatch in a tertiary care hospital in coastal Karnataka – A prospective study.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 67
- 试验地点
- 1
- 主要终点
- SWI-DWI mismatch is a substitute for PWI-DWI mismatch in the quantification of ischemic penumbra – yes/no.
研究概览
简要总结
MRI sequences as per departmental stroke protocol will be acquired for 67 patients presenting with acute ischemic stroke. The acquired data will undergo post-processing in a semi-automated software to give the following values: ischemic penumbra volume using SWI-DWI mismatch and PWI-DWI mismatch and the data will be further analyzed to evaluate the ability of SWI-DWI mismatch to identify potentially salvageable brain tissue as compared to PWI-DWI mismatch. Follow up of course of treatment of the participants post quantification of ischemic penumbra using SWI-DWI mismatch and its impact on their prognosis will be assessed.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •Stroke symptoms lasting more than 1 hour and less than 6 hours
- •NIHSS score more than 4.
排除标准
- •Patients with haemorrhagic stroke
- •Intra-cranial space occupying lesion
- •General contra-indications to MRI.
结局指标
主要结局
SWI-DWI mismatch is a substitute for PWI-DWI mismatch in the quantification of ischemic penumbra – yes/no.
时间窗: Within 1 to 6 hours of onset of acute ischemic stroke.
次要结局
- Thrombolysis post quantification of ischemic penumbra using SWI-DWI mismatch plays a significant role in improving the prognosis of patients – yes/no.
研究者
Dr Anukriti Jain
Kasturba Medical College, Manipal