The effect of vitamin D on the treatment of prostate hypertrophy
- Conditions
- Benign prostatic hypertrophy.Benign Prostatic Hypertrophy
- Registration Number
- IRCT20180922041089N3
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 54
Man over 50 years old
Asymptomatic or mild symptoms of benign prostatic hypertrophy based on the IPSS questionnaire.
Patients with benign prostatic hypertrophy
BMI greater than 35 or pathologic weight loss (weight loss over 10% of body weight in the last 6 months)
History of kidney stones, bladder and urinary tract
Having prostate or bladder cancer or prostate surgery
Acute or chronic prostatitis or frequent urinary tract infections•
History of acute urinary retention or repeated catheters in the last three months
Use of GnRH agonists, anti-androgens and any hormonal drug in the past six months, the use of herbal and non-herbal medicines to control and treat BPH
The history of chronic diseases such as CVA, HTN, COPD, liver and kidney disease, and cancers ..
Taking medications that affect vitamin D metabolism such as corticosteroids, phenytoin, phenobarbital, or regular use of vitamin D supplements over the past 3 months
Taking diuretics such as Lasix and ...
Alcohol consumption
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Prostate Volume. Timepoint: At the beginning of the study and six months later. Method of measurement: sonography.
- Secondary Outcome Measures
Name Time Method Severity of clinical symptoms. Timepoint: At the beginning of the study, 3 months later, 6 months later. Method of measurement: IPSS questionnaire.;PSA. Timepoint: At the beginning of the study, 3 months later, 6 months later. Method of measurement: laboratory kit.;Vitamin D. Timepoint: At the beginning of the study, 3 months later, 6 months later. Method of measurement: blood test.