Study of biliary microbiome in liver transplantatio
- Conditions
- end stage liver disease
- Registration Number
- DRKS00020742
- Lead Sponsor
- Klinik für Allgemein-, Viszeral- und Transplantationschirurgie LMU, Klinikum der Universität München Campus Großhadern
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
patients >18 years
patients able to give informed consent
signed informed consent
signed informed consent for biobanking
end stage liver disease with need and organ availability for liver transplantation
Exclusion Criteria
patients < 18 years
patients not able to give informed consent
patients without liver Transplantation
patients without informed consent for biobanking
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method changes of the biliary microbiota follwing liver transplantation (diversity, UniFrac Analysis, principal coordinate Analysis)
- Secondary Outcome Measures
Name Time Method Evaluation of biliary microbiome of donor vs. recipient (OTUs, diversity, PCoA)<br><br>Evaluation of conventional microbial swabs<br><br>correlation of biliary and fecal and salivary microbiome to clinical data<br><br><br>