MedPath

To Evaluate the Pharmacokinetic Characteristics and Safety in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Reference Drug or Test Drug
Registration Number
NCT06361277
Lead Sponsor
JW Pharmaceutical
Brief Summary

The objective is to evaluate the safety and pharmacokinetic characteristics after co-administration of JW0202 and C2202 and co-administration of C2205 and JW0201 in healthy volunteers under fasting conditions

Detailed Description

Pharmacokinetic characteristics: Describes the blood concentration statistically by pharmacokinetic blood collection time and treatment group.

Safety: All adverse events are summarized in terms of the number of subjects, expression rate, and number of expressions of adverse reactions by treatment group.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
56
Inclusion Criteria
  • Healthy volunteers
Exclusion Criteria
  • Subjects does not meet the Inclusion Criteria

Study & Design

Study Type
INTERVENTIONAL
Study Design
SEQUENTIAL
Arm && Interventions
GroupInterventionDescription
Group 1Reference Drug or Test DrugTreatment A: Co-administration of 2 tablets of C2205 and JW0201 Treatment B: Co-administration of 2 tablets of JW0202 and C2202 Tablet, Oral, QD for 1 Day, Washout period is more than 21 days after administration
Group 2Reference Drug or Test DrugTreatment A: Co-administration of 2 tablets of C2205 and JW0201 Treatment B: Co-administration of 2 tablets of JW0202 and C2202 Tablet, Oral, QD for 1 Day, Washout period is more than 21 days after administration
Primary Outcome Measures
NameTimeMethod
AUCtDay1 0h ~ Day3 48h

Describes the blood concentration statistically by pharmacokinetic blood collection time and treatment group.

CmaxDay1 0h ~ Day3 48h

Describes the blood concentration statistically by pharmacokinetic blood collection time and treatment group.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Clinical Trial Center, Jeonbuk National University Hospital

🇰🇷

Jeonju, Korea, Republic of

© Copyright 2025. All Rights Reserved by MedPath