跳至主要内容
临床试验/NCT05694559
NCT05694559招募中不适用

Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and Telegenetics

M.D. Anderson Cancer Center1 个研究点 分布在 1 个国家目标入组 1,000 人开始时间: 2022年11月23日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
1,000
试验地点
1
主要终点
genetic risk screening tool (GRST) questionnaire

研究概览

简要总结

To identify Black individuals who are eligible for genetic testing through trusted community organizations, and to connect Black individuals and their families to genetic testing and counseling so that they can know their cancer risk and how to decrease it.

详细描述

Primary Objectives:

  • To identify 300 Black families, at least one individual per family, eligible for genetic testing using our validated simple genetic risk screening tool (GRST) 1, via collaboration with trusted community organizations. For individuals eligible for genetic testing, we will counsel them about genetic testing, including reviewing GRST results, explaining why they are eligible for genetic testing as part of standard-of-care, explaining what this entails, offering on-site or remote genetic testing, and explaining that they will be connected to a genetic counselor if they have a pathogenic mutation (PV) of a variant of unknown significance (VUS), including resources for family cascade genetic testing.
  • To provide genetic testing to 150 Black individuals and families and provide genetic counseling and risk reduction resources to individuals with a PV or VUS, including cascade genetic testing for their family members.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Single Group
主要目的
Screening
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Any participant over 18 years old who self-identifies as Black or African-American and signs an informed consent form, also referred to as the 'Permission to Contact' form, to be part of our study.

排除标准

  • 未提供

研究组 & 干预措施

Genetic Testing and Counseling

Experimental

Participants will be given a saliva collection kit to collect a saliva sample for hereditary cancer and genetic testing.

干预措施: Genetic Testing and Counseling (Behavioral)

Screening Form

Experimental

Participants will complete a screening form to assess your risk of hereditary breast and colorectal cancers. You will be asked to provide your:

  • Name and contact information (including your address, phone number, and email)
  • Demographic information (including your age, race, and ethnicity)
  • Health insurance status
  • Annual household income
  • Personal and family history of cancer, including diagnosis and age at diagnosis

干预措施: Screening Form (Behavioral)

结局指标

主要结局

genetic risk screening tool (GRST) questionnaire

时间窗: through study completion; an average of 1 year.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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