Collecting and Storing Tissue Samples From Patients With Head and Neck Cancer
- Conditions
- Head and Neck Cancer
- Interventions
- Other: biologic sample preservation procedureProcedure: biopsy
- Registration Number
- NCT00898300
- Lead Sponsor
- Radiation Therapy Oncology Group
- Brief Summary
RATIONALE: Collecting and storing samples of tissue, blood, and saliva from patients with cancer to study in the laboratory may help the study of cancer in the future.
PURPOSE: This laboratory study is collecting and storing tissue samples from patients with head and neck cancer.
- Detailed Description
OBJECTIVES:
* Establish a tissue/specimen bank of biologic specimens collected from patients with proven or suspected head and neck cancer.
* Establish a database to link materials acquisition and pathologic and clinical information on these patients.
* Correlate clinical-pathological findings on these patients with future scientific studies using the patient database.
* Test new hypotheses as they emerge.
OUTLINE: This is a prospective, multicenter study.
Patients enrolled on active Radiation Therapy Oncology Group clinical trials undergo biopsy or surgical resection of head and neck tumors or premalignant lesions at participating institutions. Tissue and other specimens collected at the time of biopsy or surgery are submitted to the Head and Neck Cancer Tissue/Specimen Bank which acts as a central repository for processing, storing, and preserving patient specimens for translational research. Tissue samples include paraffin-embedded blocks or fresh or frozen samples of normal squamous mucosa, tumors, or premalignant lesions of the upper aerodigestive tract. Other specimens for tissue banking include serum, plasma, and lymphocytes isolated from peripheral blood, as well as samples of patient saliva. Cells obtained from tissue bank specimens may also be used to establish cell lines for future research.
PROJECTED ACCRUAL: An unlimited number of specimens will be accrued for this study.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 351
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Patients with confirmed or suspected head and neck cancer biologic sample preservation procedure - Patients with confirmed or suspected head and neck cancer biopsy -
- Primary Outcome Measures
Name Time Method Establishment of a Head and Neck Cancer Tissue/Specimen Bank From the start of enrollment to the end of enrollment; enrollment closed at 351 patients
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (98)
Val and Ann Browning Cancer Center at McKay-Dee Hospital Center
🇺🇸Ogden, Utah, United States
Gibbs Regional Cancer Center at Spartanburg Regional Medical Center
🇺🇸Spartanburg, South Carolina, United States
University of California Davis Cancer Center
🇺🇸Sacramento, California, United States
Penrose Cancer Center at Penrose Hospital
🇺🇸Colorado Springs, Colorado, United States
Winship Cancer Institute of Emory University
🇺🇸Altanta, Georgia, United States
Georgia Cancer Center for Excellence at Grady Memorial Hospital
🇺🇸Atlanta, Georgia, United States
Emory Crawford Long Hospital
🇺🇸Atlanta, Georgia, United States
Cancer Institute at St. John's Hospital
🇺🇸Springfield, Illinois, United States
Saint John's Cancer Center at Saint John's Medical Center
🇺🇸Anderson, Indiana, United States
Mountain States Tumor Institute at St. Luke's Regional Medical Center
🇺🇸Boise, Idaho, United States
Advocate Lutheran General Cancer Care Center
🇺🇸Park Ridge, Illinois, United States
Good Samaritan Cancer Care Center at Advocate Good Samaritan Hospital
🇺🇸Downers Grove, Illinois, United States
Ingalls Cancer Care Center at Ingalls Memorial Hospital
🇺🇸Harvey, Illinois, United States
Methodist Medical Center of Illinois
🇺🇸Peoria, Illinois, United States
Menorah Medical Center
🇺🇸Overland Park, Kansas, United States
Cancer Center at Ball Memorial Hospital
🇺🇸Muncie, Indiana, United States
Shawnee Mission Medical Center
🇺🇸Shawnee Mission, Kansas, United States
West Michigan Cancer Center
🇺🇸Kalamazoo, Michigan, United States
Borgess Medical Center
🇺🇸Kalamazoo, Michigan, United States
Hickman Cancer Center at Bixby Medical Center
🇺🇸Adrian, Michigan, United States
Bronson Methodist Hospital
🇺🇸Kalamazoo, Michigan, United States
Haematology-Oncology Associates of Ohio and Michigan, PC
🇺🇸Lambertville, Michigan, United States
Heartland Regional Medical Center
🇺🇸Saint Joseph, Missouri, United States
Community Cancer Center of Monroe
🇺🇸Monroe, Michigan, United States
Mercy Memorial Hospital - Monroe
🇺🇸Monroe, Michigan, United States
Kingsbury Center for Cancer Care at Cheshire Medical Center
🇺🇸Keene, New Hampshire, United States
Mayo Clinic Cancer Center
🇺🇸Rochester, Minnesota, United States
Renown Institute for Cancer at Renown Regional Medical Center
🇺🇸Reno, Nevada, United States
Truman Medical Center - Hospital Hill
🇺🇸Kansas City, Missouri, United States
Saint Luke's Cancer Institute at Saint Luke's Hospital
🇺🇸Kansas City, Missouri, United States
Parvin Radiation Oncology
🇺🇸Kansas City, Missouri, United States
CCOP - Kansas City
🇺🇸Kansas City, Missouri, United States
Research Medical Center
🇺🇸Kansas City, Missouri, United States
Presbyterian Cancer Center at Presbyterian Hospital
🇺🇸Charlotte, North Carolina, United States
Wayne Memorial Hospital, Incorporated
🇺🇸Goldsboro, North Carolina, United States
St. Joseph Medical Center
🇺🇸Kansas City, Missouri, United States
North Kansas City Hospital
🇺🇸Kansas City, Missouri, United States
Good Samaritan Cancer Center at Good Samaritan Hospital
🇺🇸Kearney, Nebraska, United States
Methodist Estabrook Cancer Center
🇺🇸Omaha, Nebraska, United States
Beth Israel Medical Center - Petrie Division
🇺🇸New York, New York, United States
Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center
🇺🇸Lebanon, New Hampshire, United States
Monmouth Medical Center
🇺🇸Long Branch, New Jersey, United States
Saint Peter's University Hospital
🇺🇸New Brunswick, New Jersey, United States
Roswell Park Cancer Institute
🇺🇸Buffalo, New York, United States
Rutherford Hospital
🇺🇸Rutherfordton, North Carolina, United States
Wood County Oncology Center
🇺🇸Bowling Green, Ohio, United States
Wayne Radiation Oncology
🇺🇸Goldsboro, North Carolina, United States
North Coast Cancer Care - Clyde
🇺🇸Clyde, Ohio, United States
Hematology Oncology Center
🇺🇸Elyria, Ohio, United States
Lima Memorial Hospital
🇺🇸Lima, Ohio, United States
Northwest Ohio Oncology Center
🇺🇸Maumee, Ohio, United States
St. Luke's Hospital
🇺🇸Maumee, Ohio, United States
Toledo Clinic - Oregon
🇺🇸Oregon, Ohio, United States
Toledo Hospital
🇺🇸Toledo, Ohio, United States
St. Charles Mercy Hospital
🇺🇸Oregon, Ohio, United States
Fisher-Titus Medical Center
🇺🇸Norwalk, Ohio, United States
North Coast Cancer Care, Incorporated
🇺🇸Sandusky, Ohio, United States
Flower Hospital Cancer Center
🇺🇸Sylvania, Ohio, United States
Mercy Hospital of Tiffin
🇺🇸Tiffin, Ohio, United States
AnMed Cancer Center
🇺🇸Anderson, South Carolina, United States
CCOP - Toledo Community Hospital
🇺🇸Toledo, Ohio, United States
American Fork Hospital
🇺🇸American Fork, Utah, United States
St. Vincent Mercy Medical Center
🇺🇸Toledo, Ohio, United States
Medical University of Ohio Cancer Center
🇺🇸Toledo, Ohio, United States
Toledo Clinic, Incorporated - Main Clinic
🇺🇸Toledo, Ohio, United States
Fulton County Health Center
🇺🇸Wauseon, Ohio, United States
Fox Chase Cancer Center - Philadelphia
🇺🇸Philadelphia, Pennsylvania, United States
St. Anne Mercy Hospital
🇺🇸Toledo, Ohio, United States
Providence Milwaukie Hospital
🇺🇸Milwaukie, Oregon, United States
Albert Einstein Cancer Center
🇺🇸Philadelphia, Pennsylvania, United States
CCOP - Upstate Carolina
🇺🇸Spartanburg, South Carolina, United States
Sandra L. Maxwell Cancer Center
🇺🇸Cedar City, Utah, United States
McGill Cancer Centre at McGill University
🇨🇦Montreal, Quebec, Canada
University of Wisconsin Paul P. Carbone Comprehensive Cancer Center
🇺🇸Madison, Wisconsin, United States
Medical College of Wisconsin Cancer Center
🇺🇸Milwaukee, Wisconsin, United States
Dixie Regional Medical Center - East Campus
🇺🇸Saint George, Utah, United States
Fredericksburg Oncology, Incorporated
🇺🇸Fredericksburg, Virginia, United States
Southwest Washington Medical Center Cancer Center
🇺🇸Vancouver, Washington, United States
Norris Cotton Cancer Center - North
🇺🇸Saint Johnsbury, Vermont, United States
John H. Stroger, Jr. Hospital of Cook County
🇺🇸Chicago, Illinois, United States
Rush University Medical Center
🇺🇸Chicago, Illinois, United States
Boston University Cancer Research Center
🇺🇸Boston, Massachusetts, United States
St. Vincent Oncology Center
🇺🇸Indianapolis, Indiana, United States
M. D. Anderson Cancer Center at University of Texas
🇺🇸Houston, Texas, United States
UAB Comprehensive Cancer Center
🇺🇸Birmingham, Alabama, United States
Barbara Ann Karmanos Cancer Institute
🇺🇸Detroit, Michigan, United States
Oklahoma University Cancer Institute
🇺🇸Oklahoma City, Oklahoma, United States
Providence Cancer Center at Providence Portland Medical Center
🇺🇸Portland, Oregon, United States
Adventist Medical Center
🇺🇸Portland, Oregon, United States
CCOP - Columbia River Oncology Program
🇺🇸Portland, Oregon, United States
Providence St. Vincent Medical Center
🇺🇸Portland, Oregon, United States
Veterans Affairs Medical Center - Portland
🇺🇸Portland, Oregon, United States
LDS Hospital
🇺🇸Salt Lake City, Utah, United States
Utah Cancer Specialists at UCS Cancer Center
🇺🇸Salt Lake City, Utah, United States
M.D. Anderson Cancer Center at Orlando
🇺🇸Orlando, Florida, United States
James Graham Brown Cancer Center at University of Louisville
🇺🇸Louisville, Kentucky, United States
Jon and Karen Huntsman Cancer Center at Intermountain Medical Center
🇺🇸Murray, Utah, United States
Utah Valley Regional Medical Center - Provo
🇺🇸Provo, Utah, United States