Dynamic Arterial Elastance to Predict Postural Change Induced Hypotension

Completed

• Conditions: Hypotension

• Registration Number: NCT04850092
• Lead Sponsor: Kangbuk Samsung Hospital

Brief Summary

During general anesthesia, hypotension might occur during positional change. It is reported that hypotension after positional change from supine to prone is mainly caused by the decrease in preload. The investigators aimed to investigate whether dynamic arterial elastance might predict hypotension associated with positional change from supine to prone.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-04-14
• Study First Submitted QC: 2021-04-14
• Study First Posted: 2021-04-20
• Study Start: 2021-12-15
• Primary Completion: 2022-07-15
• Study Completion: 2022-07-15
• Status Verified: 2022-09
• Last Update Submitted: 2022-09-21
• Last Update Posted: 2022-09-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

• Patients planned for invasive arterial catheter insertion, undergoing elective spine surgery in prone position under general anesthesia

Exclusion Criteria

• arrythmia
• pulmonary disease
• increased intracranial pressure
• decreased cardiac function (ejection fraction < 50%)
• obesity (body mass index > 40)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Dynamic arterial elastance before positional change	1 minute before positional change	Dynamic arterial elastance, defined as the ratio of pulse pressure variance/stroke volume variance will be recorded 1 minute before positional change

Trial Locations

Locations (1)

Kangbuk Samsung Hospital; 🇰🇷 Seoul, Korea, Republic of